Neurovascular Factors in Wound Healing in the Foot Skin of Type 2 Diabetic Subjects

Response to Krishnan et al.

  1. Sergiu-Bogdan Catrina, MD, PHD and
  2. Kerstin Brismar, MD, PHD
  1. From the Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
  1. Address correspondence to Sergiu-Bogdan Catrina, MD, PhD, Molecular Medicine and Surgery, Karolinska Hospital, Rolf Luft Center, Stockholm S-17176, Sweden. E-mail: sergiu-bogdan.catrina{at}ki.se

We read with interest the article by Krishnan et al. (1) reporting the healing of acute wounds in type 2 diabetic patients versus control subjects. The authors also reported the expression of vascular endothelial growth factor (VEGF)-A, VEGF-R2, and hypoxia-inducible factor (HIF)-1α in intact skin biopsies from …

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