Can Self-Rated Health Scores Be Used for Risk Prediction in Patients With Type 2 Diabetes?

  1. Alison J. Hayes, PHD1,
  2. Philip M. Clarke, PHD1,
  3. Paul G. Glasziou, PHD2,
  4. R. John Simes, FRACP3,
  5. Paul L. Drury, FRACP4 and
  6. Anthony C. Keech, FRACP3
  1. 1School of Public Health, University of Sydney, Sydney, New South Wales, Australia
  2. 2Department of Primary Care, University of Oxford, Oxford, U.K
  3. 3National Health & Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia
  4. 4Auckland Diabetes Centre, Auckland, New Zealand
  1. Address correspondence and reprint requests to Dr. Alison Hayes, School of Public Health, University of Sydney, NSW 2006 Australia. E-mail: alisonh{at}health.usyd.edu.au

Abstract

OBJECTIVE—To investigate whether self-rated health profiles compiled using the EuroQol group’s visual analog scale (EQ VAS) are independent predictors of vascular events and major complications in people with type 2 diabetes after controlling for standard clinical risk factors.

RESEARCH DESIGN AND METHODS—The study is based on 7,348 individuals with a mean follow-up of 2.4 years after completing the EQ-5D questionnaire. We used Cox proportional hazards modeling to estimate hazard ratios associated with EQ VAS scores after controlling for baseline covariates: age, sex, smoking status, diabetes duration, A1C, systolic blood pressure, BMI, plasma lipids, and prior clinical history.

RESULTS—A 10-point higher EQ VAS score was associated with a 6% (95% CI 1–11) lower risk of vascular events and a 22% (95% CI 15–28) lower risk of diabetesc complications.

CONCLUSIONS—Self-rated health profiles compiled using the EQ VAS provide valuable information on patient risk in addition to that determined from clinical risk factors alone.

Footnotes

  • Published ahead of print at http://care.diabetesjournals.org on 9 January 2008. DOI: 10.2337/dc07-1391.

    Additional information for this article can be found in an online appendix at http://dx.doi.org/10.2337/dc07-1391.

    The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C Section 1734 solely to indicate this fact.

    • Accepted December 27, 2007.
    • Received July 19, 2007.
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  1. Published online before print January 9, 2008, doi: 10.2337/dc07-1391 Diabetes Care April 2008 vol. 31 no. 4 795-797
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