Uric Acid Indicates a High Cardiovascular Risk Profile but Is Not Closely Associated With Insulin Resistance in Obese Adolescents
- Harald Mangge, MD1,
- Stefan Pilz, MD2,
- Samih Haj-Yahya, MD1 and
- Gunter Almer, MAG, MD1
- 1Department of Laboratory Medicine, Medical University of Graz, Graz, Austria
- 2Department of Public Health, Mannheim, Germany
- Address correspondence to Harald Mangge, MD, Department of Laboratory Medicine, Medical University of Graz, A-8036 Graz, Austria. E-mail: harald.mangge{at}klinikum-graz.at
We comment on a recent study by Dehghan et al. (1), who identified high serum uric acid as an independent risk factor for type 2 diabetes in adults. We investigated serum levels of uric acid in a large cohort of obese adolescents (n = 355; mean ± SD age 13.1 ± 4.1 years and age range 10–22 years) and normal-weight control subjects (n = 200) of …
