Serum Levels of Adipokine Retinol-Binding Protein-4 in Relation to Renal Function
Response to Ziegelmeier et al.
- Vasileios Papavasileiou, MD1,
- Vasilios Liakopoulos, MD, PHD1,
- Georgios K. Sakkas, PHD1,
- Georgios M. Hadjigeorgiou, MD, PHD1,
- Georgios Koukoulis, MD, PHD2 and
- Ioannis Stefanidis, MD, PHD1
- 1Department of Nephrology, University of Thessaly, School of Medicine, Larissa, Greece
- 2Department of Endocrinology, University of Thessaly, School of Medicine, Larissa, Greece
- Address correspondence to Ioannis Stefanidis, MD, PhD, Department of Nephrology , University Hospital of Larissa, Mezourlo Hill, 41110 Larissa, Greece. E-mail: stefanid{at}med.uth.gr
In their recent study, Ziegelmeier et al. (1) showed that remnant kidney function and C-reactive protein are independently associated with elevated serum levels of retinol-binding protein (sRBP)-4 in hemodialysis patients. Markers of kidney function were levels of serum creatinine and glomerular filtration rate estimated by the Cockroft-Gault formula . However, since creatinine can be removed both by dialysis and remnant kidneyfunction, levels of serum creatinine and glomerular filtration rate estimated by the Cockroft-Gault formula do not exactly reflect renal function in …
