Psoriatic Exacerbation Associated With Insulin Therapy
- Allan F. Moore, MD1,
- Tiffany Soper, RN1,
- Natalie Jones, PA2,
- Joop Grevelink, MD2 and
- Nicolas Abourizk, MD13
- 1Massachusetts General Hospital Diabetes Center, Massachusetts General Hospital, Boston, Massachusetts
- 2Boston Dermatology & Laser Center, Boston, Massachusetts
- 3Section of Endocrinology and Diabetes, Newton-Wellesley Hospital, Newton, Massachusetts
- Corresponding author: Allan F. Moore, MD, MGH Diabetes Center, Massachusetts General Hospital, 55 Staniford St., 3rd Floor, Boston, MA 02114. E-mail: afmoore{at}partners.org
We report the case of a 70-year-old male who presented with worsening psoriasis after initiating insulin therapy.
The patient, who had a 25-year history of type 2 diabetes with no complications and an A1C of 7.8%, took metformin for 20 years with stable umbilical psoriasis. He did not require psoriatic therapy before initiating insulin therapy.
In December 2006, the patient transitioned to glargine injections for a rising A1C. Two weeks later, psoriasis erupted on his abdomen and legs. …
