Coffee Consumption Is Associated With Higher Plasma Adiponectin Concentrations in Women With or Without Type 2 Diabetes
Response to Williams et al.
- Kazuhiko Kotani, MD, PHD12,
- Shinji Fujiwara, MD, PHD3,
- Taku Hamada, PHD1,
- Kokoro Tsuzaki, BSC1 and
- Naoki Sakane, MD, PHD1
- 1Department of Preventive Medicine and Diabetes Education, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
- 2Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, Yonago, Japan
- 3Division of Community Medicine and Family Practice, Jichi Medical University, Tochigi, Japan
- Corresponding author: Kazuhiko Kotani, MD, PHD, Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan. E-mail: kakotani{at}grape.med.tottori-u.ac.jp
Williams et al. reported that women consuming ≥4 cups of coffee daily had higher adiponectin levels than those consuming lower amounts, regardless of the presence of diabetes (1). They found that regular coffee consumption has beneficial effects on low-grade systemic inflammation and type 2 diabetes incidence and that adiponectin may be involved in the mechanism (1). Given variances in different ethnicities' social cultures regarding coffee consumption and in adiponectin levels across ethnicity (2), Williams et al.'s data should be confirmed on various populations. Also up for discussion is whether the data are applicable to men because of the sex-based differences in adiponectin …
