A New Zealand Linkage Study Examining the Associations Between A1C Concentration and Mortality

Table 3—

HRs for the association between A1C levels and mortality in a New Zealand population-based sample by cause of death

Site (ICD-9)	n	A1C levels
				<4.0%			4.0 to <5.0%			5.0 to <6.0%			6.0 to <7.0%			≥7.0%	Prior diabetes diagnosis
				n	HR (95% CI)*	n	HR (95% CI)*	n	HR (95% CI)*	n	HR (95% CI)*	n	HR (95% CI)*	n	HR (95% CI)*
All deaths	815	3	2.90 (0.91–9.19)	82	1.0†	449	1.33 (1.05–1.70)	129	2.12 (1.58–2.85)	87	2.36 (1.72–3.25)	65	5.19 (3.67–7.35)
All cancers (140–239)	262	0	‡	26	1.0†	154	1.10 (0.72–1.68)	44	1.50 (0.90–2.48)	23	1.29 (0.72–2.30)	15	2.35 (1.22–4.53)
Endocrine, nutritional & metabolic, and immunity disorders (240–279)	47	0	‡	0	‡	6	1.0†	2	1.79 (0.35–9.18)	19	27.17 (10.20–72.39)	20	90.36 (33.42–244.33)
Diseases of circulatory system (390–459)	280	1	3.95 (0.53–29.51)	20	1.0†	151	1.43 (0.89–2.30)	54	2.46 (1.44–4.19)	32	2.44 (1.37–4.35)	22	4.75 (2.53–8.92)
Ischemic heart disease (410–414)	166	1	6.26 (0.81–48.13)	13	1.0†	91	1.27 (0.71–2.30)	26	1.75 (0.88–3.49)	23	2.55 (1.26–5.16)	12	3.89 (1.72–8.77)
Other and unknown causes	226	2	4.53 (1.09–18.85)	36	1.0†	138	1.41 (0.96–2.06)	29	2.52 (1.47–4.31)	13	1.86 (0.95–3.65)	8	3.88 (1.72–8.74)

Published online before print February 25, 2008, doi: 10.2337/dc07-2374 Diabetes Care June 2008 vol. 31 no. 6 1144-1149

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