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Reversible Focal Hepatic Steatosis in Type 1 Diabetic Patients Treated With Intraperitoneal Insulin Implantable Pump Therapy

  1. Laurent Meyer, MD12,
  2. Jeremy Jeantroux, MD34,
  3. Jean Pierre Riveline, MD5,
  4. François Moreau, MD12,
  5. Sophie Boivin, MD12,
  6. Thomas Moser, MD34,
  7. Michel Pinget, MD12 and
  8. Nathalie Jeandidier, MD, PHD12
  1. 1Centre Hospitalier Régional Universitaire de Strasbourg, Service d'Endocrinologie, Diabète et Maladies Métaboliques, Hôpital Civil, Strasbourg, France
  2. 2Université Louis Pasteur, Faculté de Médecine, Strasbourg, France
  3. 3Centre Hospitalier Régional Universitaire de Strasbourg, Service de Radiologie Hôpital Civil, Strasbourg, France
  4. 4Université Louis Pasteur, Faculté de Médecine, Strasbourg, France
  5. 5Department of Diabetology, Hospital of Corbeil Essonnes, Corbeil Essonnes, France
  1. Corresponding author: Laurent Meyer, MD, Service d’Endocrinologie, Diabète et Maladies Métaboliques, Pavillon Leriche, 1 Place de l'Hôpital, 67000, Strasbourg, France. E-mail: laurent.meyer{at}chru-strasbourg.fr

Intraperitoneal insulin infusion (IPII) using implantable devices is used in treatment of hypoglycemia-prone diabetes. A 35-year-old type 1 diabetic woman had been treated with IPII for 3 years when a metabolic degradation occurred. A catheter tip obstruction wassuspected. An enhanced computed tomography (CT) scan was performed showing a subcapsular hypoattenuating region in the left lobe of the liver, consistent with focal steatosis. The catheter tip, surrounded by a thickening of tissue, stuck to the …

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