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High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes

Response to Dehghan et al.

  1. Chia-Yen Dai, MD, MS123,
  2. Wan-Long Chuang, MD, PHD23,
  3. Chi-Kong Ho, MD1,
  4. Tsan-Teng Ou, MD4,
  5. Jee-Fu Huang, MD25,
  6. Ming-Yen Hsieh, MD, MS2 and
  7. Ming-Lung Yu, MD, PHD23
  1. 1Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
  2. 2Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
  3. 3Faculty of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  4. 4Division of Rheumatology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
  5. 5Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan
  1. Corresponding author: Ming-Lung Yu, d820195{at}gmail.com

We read with interest the article by Dehghan et al. (1) that reports a study of 4,536 subjects free from diabetes at baseline and suggests that serum uric acid (sUA) is a strong and independent risk factor for diabetes with a mean follow-up of 10.1 years. To elucidate the association between sUA, diabetes, and chronic hepatitis C virus (HCV) infection, we conducted a community-based study enrolling 4,982 subjects (2,060 male, aged 56.2 ± 6.2 years); subjects with sUA levels >7.0 mg/dl for men and …

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