High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes
Response to Dehghan et al.
- Giuseppe Lippi, MD1,
- Giovanni Targher, MD2,
- Martina Montagnana, MD1,
- Gian Luca Salvagno, MD1 and
- Gian Cesare Guidi, MD1
- 1Section of Clinical Chemistry, Department of Morphological-Biomedical Sciences, University of Verona, Verona, Italy
- 2Section of Endocrinology and Metabolism Diseases, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
- Corresponding author: Giuseppe Lippi, ulippi{at}tin.it or giuseppe.lippi{at}univr.it
We read with interest the recent article by Dehghan et al. (1), who suggest that serum uric acid might be a strong and independent risk factor for diabetes. In particular, it was reported that the age- and sex-adjusted hazard ratios for diabetes were 1.30 for the 2nd quartile, 1.63 for the 3rd quartile, and 2.83 for the 4th quartile of serum uric acid, in comparison with the 1st quartile. To further investigate the association between uric acid and glucose homeostasis, we performed a retrospective analysis on the database of the Laboratory Information System of the Clinical Chemistry Laboratory at the Verona University Hospital to retrieve results …
