Increased Matrix Metalloproteinase-9 Predicts Poor Wound Healing in Diabetic Foot Ulcers
Response to Muller et al.
- Yu Liu, MD1,
- Danqing Min, PHD2,
- Thyra Bolton, RN3,
- Vanessa Nubé, MSCPOD3,
- Stephen M. Twigg, PHD, MD1,2,3,
- Dennis K. Yue, PHD, MD1,2,3 and
- Susan V. McLennan, PHD1,2
- 1Discipline of Medicine, University of Sydney, Sydney, Australia;
- 2Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, Australia;
- 3Diabetes Centre, Royal Prince Alfred Hospital, Sydney, Australia.
- Corresponding author: Susan McLennan, smclennan{at}med.usyd.edu.au.
We thank the authors for their comment (1) on our study (2) and we agree that the pathophysiology of diabetic foot ulcers is complex and not well understood. We recognize that we are not the first to establish a potential role for matrix metalloproteinase-9 (MMP-9) in chronic wound healing. However, we report that its measurement …
