Reduced 10-Year Risk of Coronary Heart Disease in Patients Who Participated in a Community-Based Diabetes Prevention Program

The DEPLOY pilot study

  1. Elaine R. Lipscomb, PHD1,
  2. Emily A. Finch, MA2,
  3. Edward Brizendine, MS2,
  4. Chandan K. Saha, PHD2,
  5. Laura M. Hays, RN, PHD3 and
  6. Ronald T. Ackermann, MD, MPH2
  1. 1Roudebush Veterans Affairs Medical Center, Health Services Research & Development Center of Excellence for Implementing Evidence-Based Practice, Indianapolis, Indiana
  2. 2Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
  3. 3School of Nursing, Indiana University, Indianapolis, Indiana
  1. Corresponding author: Elaine R. Lipscomb, elaine.lipscomb{at}va.gov

Abstract

OBJECTIVE—We evaluated whether participation in a community-based group diabetes prevention program might lead to relative changes in composite 10-year coronary heart disease (CHD) risk for overweight adults with abnormal glucose metabolism.

RESEARCH DESIGN AND METHODS—We used the UK Prospective Diabetes Study engine to estimate CHD risk for group-lifestyle and brief counseling (control) groups. Between-group risk changes after 4 and 12 months were compared using ANCOVA.

RESULTS—Baseline 10-year risk was similar between treatment groups (P = 0.667). At 4 and 12 months, the intervention group experienced significant decreases in 10-year risk from baseline (−3.28%, P < 0.001; and −2.23%, P = 0.037) compared with control subjects (−0.78%, P = 0.339; and +1.88%, P = 0.073). Between-group differences were statistically significant and increased from the 4- to 12-month visits.

CONCLUSIONS—Community-based delivery of the Diabetes Prevention Program lifestyle intervention could be a promising strategy to prevent both CHD and type 2 diabetes in adults with pre-diabetes.

Footnotes

  • Published ahead of print at http://care.diabetesjournals.org on 23 December 2008.

    Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

    The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C Section 1734 solely to indicate this fact.

    • Accepted December 15, 2008.
    • Received September 3, 2008.
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  1. Published online before print December 23, 2008, doi: 10.2337/dc08-1622 Diabetes Care March 2009 vol. 32 no. 3 394-396
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