Depression and Type 2 Diabetes Over the Lifespan: A Meta-Analysis
Response to Nouwen, Lloyd, and Pouwer
- Briana Mezuk, PHD1,
- William W. Eaton, PHD2 and
- Sherita Hill Golden, MD, MHS3,4
- 1Department of Epidemiology, University of Michigan, Ann Arbor, Michigan;
- 2Department of Mental Health, Johns Hopkins School of Public Health, Baltimore, Maryland;
- 3Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, Maryland;
- 4Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland.
- Corresponding author: Briana Mezuk, bmezuk{at}umich.edu
We appreciate the thoughtful comments of Nouwen, Lloyd, and Pouwer (1) on our recent systematic review of the bidirectional relationship between depression and type 2 diabetes (2). They criticize the choice of only including studies that excluded cases of depression at baseline from the analysis of type 2 diabetes as a risk factor for incident depression because depression is a chronic condition and the absence of baseline depression does not rule out prior episodes. We agree with the instinct to measure the lifetime history of …
