Predicting 6-Year Mortality Risk in Patients With Type 2 Diabetes
Response to Wells et al.
- Sanjoy Paul, PHD1,
- Ruth L. Coleman, MSC1,
- Hermione C. Price, MBCHB, MRCP1 and
- Andrew J. Farmer, DM, FRCGP1,2
- 1Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Oxford, U.K.;
- 2Department of Primary Health Care, University of Oxford, Oxford, U.K.
- Corresponding author: Andrew J. Farmer, andrew.farmer{at}dphpc.ox.ac.uk
In their recent report, Wells et al. (1) describe the derivation of a statistical tool designed to predict mortality risk in patients with type 2 diabetes. We have a number of concerns about the methods used and the reporting of this study. These concerns include the possibility that the extent of imputation used may have introduced bias, that the modeling is based only on baseline information, and that the report does not adequately reference prior work.
The researchers acknowledge that over 50% of some baseline characteristics …











