Prevention of Diabetes Self-Management Program (PREDIAS): Effects on Weight, Metabolic Risk Factors, and Behavioral Outcomes

doi:10.2337/dc08-2141

Prevention of Diabetes Self-Management Program (PREDIAS): Effects on Weight, Metabolic Risk Factors, and Behavioral Outcomes

¹Research Institute of the Diabetes Academy Mergentheim and Diabetes Centre Mergentheim, Bad Mergentheim, Germany;
²Department of Medicine, University of Dresden, Carl Gustav Carus, Dresden, Germany.

Corresponding author: Norbert Hermanns, hermanns{at}diabetes-zentrum.de.

Abstract

OBJECTIVE To evaluate the efficacy of the group program PREDIAS for diabetes prevention.

RESEARCH DESIGN AND METHODS PREDIAS consists of 12 lessons and aims at lifestyle modification. The control group received written information about diabetes prevention. In this study, a total of 182 persons with an elevated diabetes risk participated (aged 56.3 ± 10.1 years, 43% female, and BMI 31.5 ± 5.3 kg/m²).

RESULTS After 12 months, weight loss was significantly higher (P = 0.001) in PREDIAS than in the control group (−3.8 ± 5.2 vs. −1.4 ± 4.09 kg). There were also significant effects (P = 0.001) on fasting glucose (control group 1.8 ± 13.1 mg/dl vs. PREDIAS −4.3 ± 11.3 mg/dl), duration of physical activity per week (control group 17.9 ± 63.8 min vs. PREDIAS 46.6 ± 95.5 min; P = 0.03), and eating behavior.

CONCLUSIONS PREDIAS significantly modified lifestyle factors associated with an elevated diabetes risk.

Footnotes

Clinical trial reg. no. NCT00707447, clinicaltrials.gov.
The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
- Received December 2, 2008.
- Accepted March 6, 2009.
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