Five-Year Change in Visceral Adipose Tissue Quantity in a Minority Cohort: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
- Kristen G. Hairston, MD, MPH1,
- Ann Scherzinger, PHD2,
- Capri Foy, PHD1,
- Anthony J. Hanley, PHD3,
- Orita McCorkle1,
- Steven Haffner, MD, MPH4,
- Jill M. Norris, MPH, PHD2,
- Michael Bryer-Ash, MD5 and
- Lynne E. Wagenknecht, DRPH1
- 1Wake Forest University School of Medicine, Winston-Salem, North Carolina;
- 2University of Colorado Health Sciences Center, Denver, Colorado;
- 3Department of Nutritional Sciences, University of Toronto, Toronto, Canada;
- 4University of Texas Health Science Center at San Antonio, San Antonio, Texas;
- 5University of Oklahoma School of Health Sciences, Oklahoma City, Oklahoma.
- Corresponding author: Kristen G. Hairston, kghairst{at}wfubmc.edu.
Abstract
OBJECTIVE To describe the 5-year change in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) areas.
RESEARCH DESIGN AND METHODS Absolute change in VAT and SAT measured by abdominal computed tomography scans has been obtained at a 5-year interval from African Americans (n = 389) and Hispanic Americans (n = 844), aged 20–69 years, in 10-year age-groups.
RESULTS Mean 5-year increases in VAT areas in women were 18, 7, 4, 0.4, and −3 cm2 for African Americans and 13, 7, 3, 1, and −15 cm2 for Hispanics, across the 5 age decades (trend not significant). Mean 5-year increases in SAT areas in women were 88, 46, 19, 17, and 14 cm2 for African Americans and 53, 20, 17, 12, and 1 cm2 for Hispanics, across the 5 age decades (P < 0.05 for both). Similar trends have been observed in men.
CONCLUSIONS Accumulation of abdominal fat is greatest in young adulthood. These data may be useful in identifying subgroups at risk of type 2 diabetes.
Footnotes
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- Received February 19, 2009.
- Accepted May 13, 2009.
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Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.
- © 2009 by the American Diabetes Association.
