Validation of Diabetes Risk Scores for Predicting Diabetes Diagnosed by Oral Glucose Tolerance Test
- Hung-Yuan Li, MD1,2,
- Yi-Cheng Chang, MD3,
- Jung-Nan Wei, PHD4 and
- Lee-Ming Chuang, MD, PHD1,2,5
- 1Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan;
- 2Graduate Institute of Clinical Medicine, Medical College, National Taiwan University, Taipei, Taiwan;
- 3Genomics Research Center, Academia Sinica, Taipei, Taiwan;
- 4Chia Nan University of Pharmacy and Science, Tainan, Taiwan;
- 5Graduate Institute of Preventive Medicine, National Taiwan University School of Public Health, Taipei, Taiwan.
- Corresponding author: Lee-Ming Chuang, leeming{at}ntu.edu.tw.
Recently, we have reported a study evaluating the performance of 11 diabetes risk scores (DRSs) to find subjects with diabetes, metabolic syndrome, and chronic kidney diseases (1), including a DRS developed by that database (DRS-Lin), i.e., in male subjects, x = −8.3805 + age*0.0325 + waist circumference*0.0423 + 0.5866 if using hypertension drugs + 0.2429 if there was a positive diabetes family history; in female subjects, x = −9.523 + age*0.0446 + waist circumference*0.0468 + 0.4264 if using hypertension drugs + 0.5060 if there was a positive diabetes family history; risk of diabetes = 1/(1 + e−x). In that report, diabetes was diagnosed based on fasting plasma glucose instead of a 75-g oral …
