Association of Vitamin D With Insulin Resistance and β-Cell Dysfunction in Subjects at Risk for Type 2 Diabetes
Response to Muscogiuri et al.
- Sheena Kayaniyil, MSC1,
- Ravi Retnakaran, MD2,
- Julia A. Knight, PHD3,4,
- Ying Qi, MSC2,
- Bruce A. Perkins, MD2,
- Stewart B. Harris, MD5,
- Bernard Zinman, MD2,4 and
- Anthony J. Hanley, PHD1,2,3
- 1Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada;
- 2Division of Endocrinology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada;
- 3Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada;
- 4Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada;
- 5Centre for Studies in Family Medicine, University of Western Ontario, London, Ontario, Canada.
- Address correspondence to: Anthony Hanley, .
We thank Muscogiuri et al. (1) for their insightful comments regarding our study and appreciate the opportunity to address them. Muscogiuri et al. suggest that our study sample primarily consisted of obese subjects, as the mean BMI of our subjects was 30.5 kg/m2. In fact, BMI ranged from 18.2 to 60.1 kg/m2, and 28% had a BMI <27 kg/m2. Thus, our study subjects represented a broad range of body mass.
Muscogiuri et al. further suggest that …