Effect of Internet Therapeutic Intervention on A1C Levels in Patients With Type 2 Diabetes Treated With Insulin

  1. Stuart A. Ross, MD3
  1. 1Department of Endocrinology and Metabolism, St. Paul's Hospital, Vancouver, British Columbia, Canada;
  2. 2University of British Columbia, Vancouver, British Columbia, Canada;
  3. 3Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
  1. Corresponding author: Hugh D. Tildesley, hught{at}


OBJECTIVE To assess the effect of an Internet-based glucose monitoring system (IBGMS) on A1C levels in patients with type 2 diabetes treated with insulin.

RESEARCH DESIGN AND METHODS This trial involved 50 patients randomly assigned to receive either conventional treatment alone or with additional follow-up through an IBGMS for 6 months. Patients randomized to the intervention group uploaded blood glucose readings every 2 weeks to a secure Web site for review and receipt of feedback from their endocrinologist. A1C and laboratory test results were collected at 0, 3, and 6 months.

RESULTS The baseline parameters were not significantly different. Over a 6-month follow-up, A1C dropped from 8.8 to 7.6% (P < 0.001) in the intervention group compared with 8.5 to 8.4% (P = 0.51) in the control group.

CONCLUSIONS The use of IBGMS significantly improved A1C levels in patients with type 2 diabetes treated with insulin.


  • Clinical trial reg. no. NCT00814190,

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