Effects of a Home-Based Walking Intervention on Mobility and Quality of Life in People With Diabetes and Peripheral Arterial Disease
A randomized controlled trial
- Tracie C. Collins, MD, MPH1⇓,
- Scott Lunos, MS2,
- Teri Carlson, BA3,
- Kimberly Henderson, BA1,
- Marissa Lightbourne, MD4,
- Brittney Nelson, MA3 and
- James S. Hodges, PHD5
- 1Department of Medicine, University of Minnesota, Minneapolis, Minnesota
- 2Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota
- 3Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota
- 4Departments of Medicine and Pediatrics, Wayne State University, Detroit, Michigan
- 5Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota
- Corresponding author: Tracie C. Collins, .
OBJECTIVE Determine the efficacy of a home-based walking intervention to improve walking ability and quality of life in people with diabetes and peripheral arterial disease (PAD).
RESEARCH DESIGN AND METHODS We conducted a randomized, controlled, single-blind trial within university-affiliated clinics in our local community. We randomized 145 participants (45 women) with diabetes and PAD to our intervention—a 6-month behavioral intervention targeting levels of readiness to engage in routine walking for exercise—versus attention control. Our primary outcome was 6-month change in maximal treadmill walking distance. Secondary outcomes included 3-month change in maximal walking distance, lower limb function (i.e., walking impairment scores), quality of life (Medical Outcomes Short Form Survey), exercise behaviors, depressive symptoms, and self-efficacy at 3 and 6 months.
RESULTS The mean age of participants was 66.5 (SD 10.1) years. Intervention and control groups did not differ significantly in 6-month change in maximal treadmill walking distance (average [SE] 24.5 [19.6] meters vs. 39.2 [19.6] meters; P = 0.60). Among secondary outcomes, for the intervention and control groups, respectively, average walking speed scores increased by 5.7 [2.2] units and decreased by 1.9 [2.8] units (P = 0.03); the mental health quality of life subscale score increased by 3.2 [1.5] and decreased by 2.4 [1.5] units (P = 0.01).
CONCLUSIONS A home-based walking intervention did not improve walking distance but did improve walking speed and quality of life in people with diabetes and PAD. Clinicians should consider recommending home-based walking therapy for such patients.
- Received December 21, 2010.
- Accepted July 16, 2011.
- © 2011 by the American Diabetes Association.
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