Distribution of Abdominal Visceral and Subcutaneous Adipose Tissue and Metabolic Syndrome in a Korean Population
- Soyeun Kim, MD1,
- Belong Cho, MD, PHD2,
- Hyejin Lee, MD2,
- Kyojoo Choi, MD2,
- Seung Sik Hwang, MD, PHD3,
- Donghee Kim, MD, PHD4,
- Kyoungwoo Kim, MD5 and
- Hyuktae Kwon, MD, MPH6
- 1Department of Family Medicine, CHA Hospital Anti-Aging Institute, Seoul, South Korea
- 2Department of Family Medicine, Seoul National University College of Medicine, Seoul, South Korea
- 3Department of Social and Preventive Medicine, Inha University School of Medicine, Incheon, South Korea
- 4Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, South Korea
- 5Department of Family Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, South Korea
- 6Department of Family Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, South Korea
- Corresponding author: Hyuktae Kwon, .
OBJECTIVE This study aimed to assess the correlation between abdominal subcutaneous adipose tissue (SAT) and metabolic syndrome (MetS) in Korean adults after adjusting for the effects of visceral adipose tissue (VAT).
RESEARCH DESIGN AND METHODS The SAT/VAT ratio (SVR) was calculated using abdominal computed tomography in 2,655 subjects. We used regression analyses to assess whether the SVR predicted MetS.
RESULTS For both sexes, the prevalence of elevated triglycerides, reduced HDL, and elevated fasting glucose significantly decreased with increasing quintiles of SVR (P for trend < 0.05). The prevalence and odds ratios of MetS significantly decreased as the SVR increased (men: odds ratio 0.5 [95% CI 0.3–0.7]; women: 0.2 [0.1–0.5] for comparisons of lowest vs. highest quintile; P for trend < 0.05).
CONCLUSIONS After adjustment for VAT, abdominal SAT was inversely correlated with the occurrence of MetS.
This article contains Supplementary Data online at http://care.diabetesjournals.org/lookup/suppl/doi:10.2337/dc10-1364/-/DC1.
- Received July 15, 2010.
- Accepted November 14, 2010.
- © 2011 by the American Diabetes Association.
Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.