Diabetes Care: 37 (10)

October 01 2014; volume 37 issue 10

In This Issue

Open Access
In This Issue of Diabetes Care
Diabetes Care 2014 Oct; 37 (10): 2663-2664. https://doi.org/10.2337/dc14-ti10

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Editorial

Open Access
Joining Forces: A Call for Greater Collaboration to Study New Medicines in Children and Adolescents With Type 2 Diabetes
Janina Karres, Valerie Pratt, Jean-Marc Guettier, Jean Temeck, William V. Tamborlane, David Dunger, Cristina Bejnariu, Carine De Beaufort and Paolo Tomasi

Diabetes Care 2014 Oct; 37 (10): 2665-2667. https://doi.org/10.2337/dc14-0494

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Perspectives in Care

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We Can Change the Natural History of Type 2 Diabetes
Lawrence S. Phillips, Robert E. Ratner, John B. Buse and Steven E. Kahn

Diabetes Care 2014 Oct; 37 (10): 2668-2676. https://doi.org/10.2337/dc14-0817

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Clinical Care/Education/Nutrition/Psychosocial Research

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Higher Gestational Weight Gain Is Associated With Increasing Offspring Birth Weight Independent of Maternal Glycemic Control in Women With Type 1 Diabetes
Anna L. Secher, Clara B. Parellada, Lene Ringholm, Björg Ásbjörnsdóttir, Peter Damm and Elisabeth R. Mathiesen

Diabetes Care 2014 Oct; 37 (10): 2677-2684. https://doi.org/10.2337/dc14-0896

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Falling Insulin Requirements Are Associated With Adverse Obstetric Outcomes in Women With Preexisting Diabetes
Suja Padmanabhan, Mark McLean and N. Wah Cheung

Diabetes Care 2014 Oct; 37 (10): 2685-2692. https://doi.org/10.2337/dc14-0506

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Cultures of Diabetic Foot Ulcers Without Clinical Signs of Infection Do Not Predict Outcomes
Sue E. Gardner, Ambar Haleem, Ying-Ling Jao, Stephen L. Hillis, John E. Femino, Phinit Phisitkul, Kristopher P. Heilmann, Shannon M. Lehman and Carrie L. Franciscus

Diabetes Care 2014 Oct; 37 (10): 2693-2701. https://doi.org/10.2337/dc14-0051

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Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry
Jenise C. Wong, Nicole C. Foster, David M. Maahs, Dan Raghinaru, Richard M. Bergenstal, Andrew J. Ahmann, Anne L. Peters, Bruce W. Bode, Grazia Aleppo, Irl B. Hirsch, Lora Kleis, H. Peter Chase, Stephanie N. DuBose, Kellee M. Miller, Roy W. Beck and Saleh Adi, for the T1D Exchange Clinic Network

Diabetes Care 2014 Oct; 37 (10): 2702-2709. https://doi.org/10.2337/dc14-0303

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Diabetes-Related Distress, Insulin Dose, and Age Contribute to Insulin-Associated Weight Gain in Patients With Type 2 Diabetes: Results of a Prospective Study
Henry J. Jansen, Gerald M.M. Vervoort, Anton F.J. de Haan, Paetrick M. Netten, Wim J. de Grauw and Cees J. Tack

Diabetes Care 2014 Oct; 37 (10): 2710-2717. https://doi.org/10.2337/dc13-1205

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Open Access
Increased Circulating Levels of Betatrophin in Newly Diagnosed Type 2 Diabetic Patients
Hao Hu, Wenjun Sun, Shuqin Yu, Xiafei Hong, Weiyun Qian, Bingqian Tang, Dong Wang, Ling Yang, Jifang Wang, Caoming Mao, Libin Zhou and Guoyue Yuan

Diabetes Care 2014 Oct; 37 (10): 2718-2722. https://doi.org/10.2337/dc14-0602

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Efficacy and Safety of the Once-Weekly GLP-1 Receptor Agonist Albiglutide Versus Sitagliptin in Patients With Type 2 Diabetes and Renal Impairment: A Randomized Phase III Study
Lawrence A. Leiter, Molly C. Carr, Murray Stewart, Angela Jones-Leone, Rhona Scott, Fred Yang and Yehuda Handelsman

Diabetes Care 2014 Oct; 37 (10): 2723-2730. https://doi.org/10.2337/dc13-2855

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Epidemiology/Health Services Research

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Reduced Testing Frequency for Glycated Hemoglobin, HbA_1c, Is Associated With Deteriorating Diabetes Control
Owen J. Driskell, David Holland, Jenna L. Waldron, Clare Ford, Jonathan J. Scargill, Adrian Heald, Martin Tran, Fahmy W. Hanna, Peter W. Jones, R. John Pemberton and Anthony A. Fryer

Diabetes Care 2014 Oct; 37 (10): 2731-2737. https://doi.org/10.2337/dc14-0297

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Effects of Weight Loss, Weight Cycling, and Weight Loss Maintenance on Diabetes Incidence and Change in Cardiometabolic Traits in the Diabetes Prevention Program
Linda M. Delahanty, Qing Pan, Kathleen A. Jablonski, Vanita R. Aroda, Karol E. Watson, George A. Bray, Steven E. Kahn, Jose C. Florez, Leigh Perreault and Paul W. Franks, for the Diabetes Prevention Program Research Group

Diabetes Care 2014 Oct; 37 (10): 2738-2745. https://doi.org/10.2337/dc14-0018

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Emerging Technologies and Therapeutics

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Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes
Ronnie Aronson, Peter A. Gottlieb, Jens S. Christiansen, Thomas W. Donner, Emanuele Bosi, Bruce W. Bode, Paolo Pozzilli and the DEFEND Investigator Group

Diabetes Care 2014 Oct; 37 (10): 2746-2754. https://doi.org/10.2337/dc13-0327

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Open Access
New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 2 Diabetes Using Basal and Mealtime Insulin: Glucose Control and Hypoglycemia in a 6-Month Randomized Controlled Trial (EDITION 1)
Matthew C. Riddle, Geremia B. Bolli, Monika Ziemen, Isabel Muehlen-Bartmer, Florence Bizet and Philip D. Home, on behalf of the EDITION 1 Study Investigators

Diabetes Care 2014 Oct; 37 (10): 2755-2762. https://doi.org/10.2337/dc14-0991

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Open Access
Glucagon-Like Peptide 1 Receptor Agonist or Bolus Insulin With Optimized Basal Insulin in Type 2 Diabetes
Michaela Diamant, Michael A. Nauck, Rimma Shaginian, James K. Malone, Simon Cleall, Matthew Reaney, Danielle de Vries, Byron J. Hoogwerf, Leigh MacConell and Bruce H.R. Wolffenbuttel, for the 4B Study Group

Diabetes Care 2014 Oct; 37 (10): 2763-2773. https://doi.org/10.2337/dc14-0876

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Pathophysiology/Complications

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Renal Hyperfiltration Is Associated With Glucose-Dependent Changes in Fractional Excretion of Sodium in Patients With Uncomplicated Type 1 Diabetes
Gary K. Yang, Ronnie L.H. Har, Yuliya Lytvyn, Paul Yip and David Z.I. Cherney

Diabetes Care 2014 Oct; 37 (10): 2774-2781. https://doi.org/10.2337/dc14-0798

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Blood Pressure and Pulse Pressure Effects on Renal Outcomes in the Veterans Affairs Diabetes Trial (VADT)
Robert J. Anderson, Gideon D. Bahn, Nicholas V. Emanuele, Jennifer B. Marks and William C. Duckworth, for the VADT Study Group

Diabetes Care 2014 Oct; 37 (10): 2782-2788. https://doi.org/10.2337/dc14-0284

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Cardiovascular and Metabolic Risk

Open Access
Effect of 8 Weeks of Overfeeding on Ectopic Fat Deposition and Insulin Sensitivity: Testing the “Adipose Tissue Expandability” Hypothesis
Darcy L. Johannsen, Yourka Tchoukalova, Charmaine S. Tam, Jeffrey D. Covington, Wenting Xie, Jean-Marc Schwarz, Sudip Bajpeyi and Eric Ravussin

Diabetes Care 2014 Oct; 37 (10): 2789-2797. https://doi.org/10.2337/dc14-0761

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Contributors to Mortality in High-Risk Diabetic Patients in the Diabetes Heart Study
Amanda J. Cox, Fang-Chi Hsu, Barry I. Freedman, David M. Herrington, Michael H. Criqui, J. Jeffrey Carr and Donald W. Bowden

Diabetes Care 2014 Oct; 37 (10): 2798-2803. https://doi.org/10.2337/dc14-0081

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Lipid Profiling Reveals Different Therapeutic Effects of Metformin and Glipizide in Patients With Type 2 Diabetes and Coronary Artery Disease
Yifei Zhang, Chunxiu Hu, Jie Hong, Jun Zeng, Shenghan Lai, Ankang Lv, Qing Su, Yan Dong, Zhiguang Zhou, Weili Tang, Jiajun Zhao, Lianqun Cui, Dajin Zou, Dawang Wang, Hong Li, Chao Liu, Guoting Wu, Jie Shen, Dalong Zhu, Weiqing Wang, Weifeng Shen, Guang Ning and Guowang Xu

Diabetes Care 2014 Oct; 37 (10): 2804-2812. https://doi.org/10.2337/dc14-0090

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Increased Cardiometabolic Risk Factors and Inflammation in Adipose Tissue in Obese Subjects Classified as Metabolically Healthy
Javier Gómez-Ambrosi, Victoria Catalán, Amaia Rodríguez, Patricia Andrada, Beatriz Ramírez, Patricia Ibáñez, Neus Vila, Sonia Romero, María A. Margall, María J. Gil, Rafael Moncada, Víctor Valentí, Camilo Silva, Javier Salvador and Gema Frühbeck

Diabetes Care 2014 Oct; 37 (10): 2813-2821. https://doi.org/10.2337/dc14-0937

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The Look AHEAD Trial: Bone Loss at 4-Year Follow-up in Type 2 Diabetes
Edward W. Lipkin, Ann V. Schwartz, Andrea M. Anderson, Cralen Davis, Karen C. Johnson, Edward W. Gregg, George A. Bray, Robert Berkowitz, Anne L. Peters, Amelia Hodges, Cora Lewis, Steven E. Kahn and the Look AHEAD Research Group

Diabetes Care 2014 Oct; 37 (10): 2822-2829. https://doi.org/10.2337/dc14-0762

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Novel Communications in Diabetes

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Glycation of Fetal Hemoglobin Reflects Hyperglycemia Exposure In Utero
Felix O. Dupont, Marie-France Hivert, Catherine Allard, Julie Ménard, Patrice Perron, Luigi Bouchard, Julie Robitaille, Jean-Charles Pasquier, Christiane Auray-Blais and Jean-Luc Ardilouze

Diabetes Care 2014 Oct; 37 (10): 2830-2833. https://doi.org/10.2337/dc14-0549

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Position Statement

Open Access
Care of Young Children With Diabetes in the Child Care Setting: A Position Statement of the American Diabetes Association
Linda M. Siminerio, Anastasia Albanese-O’Neill, Jane L. Chiang, Katie Hathaway, Crystal C. Jackson, Jill Weissberg-Benchell, Janel L. Wright, Alan L. Yatvin and Larry C. Deeb

Diabetes Care 2014 Oct; 37 (10): 2834-2842. https://doi.org/10.2337/dc14-1676

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Scientific Statement

Open Access
Type 1 Diabetes Mellitus and Cardiovascular Disease: A Scientific Statement From the American Heart Association and American Diabetes Association
Sarah D. de Ferranti, Ian H. de Boer, Vivian Fonseca, Caroline S. Fox, Sherita Hill Golden, Carl J. Lavie, Sheela N. Magge, Nikolaus Marx, Darren K. McGuire, Trevor J. Orchard, Bernard Zinman and Robert H. Eckel

Diabetes Care 2014 Oct; 37 (10): 2843-2863. https://doi.org/10.2337/dc14-1720

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Consensus Report

Open Access
Diabetic Kidney Disease: A Report From an ADA Consensus Conference
Katherine R. Tuttle, George L. Bakris, Rudolf W. Bilous, Jane L. Chiang, Ian H. de Boer, Jordi Goldstein-Fuchs, Irl B. Hirsch, Kamyar Kalantar-Zadeh, Andrew S. Narva, Sankar D. Navaneethan, Joshua J. Neumiller, Uptal D. Patel, Robert E. Ratner, Adam T. Whaley-Connell and Mark E. Molitch

Diabetes Care 2014 Oct; 37 (10): 2864-2883. https://doi.org/10.2337/dc14-1296

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Review

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The Effects of Dipeptidyl Peptidase-4 Inhibition on Microvascular Diabetes Complications
Angelo Avogaro and Gian Paolo Fadini

Diabetes Care 2014 Oct; 37 (10): 2884-2894. https://doi.org/10.2337/dc14-0865

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Erratum

Open Access
Efficacy and Safety of Dulaglutide Added Onto Pioglitazone and Metformin Versus Exenatide in Type 2 Diabetes in a Randomized Controlled Trial (AWARD-1). Diabetes Care 2014;37:2159–2167
Carol Wysham, Thomas Blevins, Richard Arakaki, Gildred Colon, Pedro Garcia, Charles Atisso, Debra Kuhstoss and Mark Lakshmanan

Diabetes Care 2014 Oct; 37 (10): 2895. https://doi.org/10.2337/dc14-er10

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Issues and Events

Open Access
Issues and Events
Diabetes Care 2014 Oct; 37 (10): 2896. https://doi.org/10.2337/dc14-ie10

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e-Letters

Observations
- Open Access
  Dry Eye Syndrome in Subjects With Diabetes and Association With Neuropathy
  Vasilis Achtsidis, Ioanna Eleftheriadou, Eleftheria Kozanidou, Konstantine I. Voumvourakis, Eleftherios Stamboulis, Panos G. Theodosiadis and Nicholas Tentolouris
  
  Diabetes Care 2014 Oct; 37 (10): e210-e211. https://doi.org/10.2337/dc14-0860
  
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- Open Access
  Glycemic Control in Diabetic Patients With Impaired Endogenous Insulin Secretory Capacity Is Vulnerable After a Natural Disaster: Study of Great East Japan Earthquake
  Mamiko Tanaka, Junta Imai, Michihiro Satoh, Takanao Hashimoto, Tomohito Izumi, Shojiro Sawada, Kenji Uno, Yutaka Hasegawa, Keizo Kaneko, Tetsuya Yamada, Yasushi Ishigaki, Yutaka Imai and Hideki Katagiri
  
  Diabetes Care 2014 Oct; 37 (10): e212-e213. https://doi.org/10.2337/dc14-1479
  
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- Open Access
  Latent Autoimmune Diabetes in Stiff-Person Syndrome
  Spiros Fourlanos, Andrew Neal, Michelle So and Andrew Evans
  
  Diabetes Care 2014 Oct; 37 (10): e214-e215. https://doi.org/10.2337/dc14-1444
  
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Comments and Responses
- Open Access
  Comment on Bordeleau et al. The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia. Diabetes Care 2014;37:1360–1366
  Samy Suissa and Laurent Azoulay
  
  Diabetes Care 2014 Oct; 37 (10): e216. https://doi.org/10.2337/dc14-1075
  
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- Open Access
  Response to Suissa and Azoulay. The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia. Diabetes Care 2014;37:1360–1366
  Louise Bordeleau and Hertzel C. Gerstein
  
  Diabetes Care 2014 Oct; 37 (10): e217. https://doi.org/10.2337/dc14-1220
  
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- Open Access
  Comment on Sarkar et al. Exenatide Treatment for 6 Months Improves Insulin Sensitivity in Adults With Type 1 Diabetes. Diabetes Care 2014;37:666–670
  Ajay Chaudhuri, Nitesh Kuhadiya, Husam Ghanim and Paresh Dandona
  
  Diabetes Care 2014 Oct; 37 (10): e218. https://doi.org/10.2337/dc14-1052
  
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- Open Access
  Response to Comment on Sarkar et al. Exenatide Treatment for 6 Months Improves Insulin Sensitivity in Adults With Type 1 Diabetes. Diabetes Care 2014;37:666–670
  Gayatri Sarkar, May Alattar, Rebecca J. Brown, Michael J. Quon, David M. Harlan and Kristina I. Rother
  
  Diabetes Care 2014 Oct; 37 (10): e219-e220. https://doi.org/10.2337/dc14-1482
  
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- Open Access
  Comment on Bordeleau et al. The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia. Diabetes Care 2014;37:1360–1366
  Marjolein M.J. Zanders, Andrew G. Renehan, Samantha L. Bowker, Bendix Carstensen, Lonneke V. van de Poll-Franse and Jeffrey A. Johnson
  
  Diabetes Care 2014 Oct; 37 (10): e221-e222. https://doi.org/10.2337/dc14-1380
  
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- Open Access
  Response to Zanders et al. The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia. Diabetes Care 2014;37:1360–1366
  Louise Bordeleau and Hertzel C. Gerstein
  
  Diabetes Care 2014 Oct; 37 (10): e223. https://doi.org/10.2337/dc14-1567
  
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- Open Access
  Comment on Kramer et al. Glucagon Response to Oral Glucose Challenge in Type 1 Diabetes: Lack of Impact of Euglycemia. Diabetes Care 2014;37:1076–1082
  Nobuyuki Takahashi, Tetsuro Tsujimoto and Hiroshi Kajio
  
  Diabetes Care 2014 Oct; 37 (10): e224. https://doi.org/10.2337/dc14-1500
  
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- Open Access
  Response to Comment on Kramer et al. Glucagon Response to Oral Glucose Challenge in Type 1 Diabetes: Lack of Impact of Euglycemia. Diabetes Care 2014;37:1076–1082
  Caroline K. Kramer, Ravi Retnakaran and Bernard Zinman
  
  Diabetes Care 2014 Oct; 37 (10): e225. https://doi.org/10.2337/dc14-1636
  
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- Open Access
  Comment on Doyle et al. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care 2014;37:1191–1197
  Nick S. Oliver, Mark L. Evans, Roman Hovorka, Simon Heller, Desmond G. Johnston, Stephanie A. Amiel and Katharine Barnard
  
  Diabetes Care 2014 Oct; 37 (10): e226-e227. https://doi.org/10.2337/dc14-1499
  
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- Open Access
  Response to Comment on Doyle et al. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care 2014;37:1191–1197
  Francis J. Doyle III, Lauren M. Huyett, Joon Bok Lee, Howard C. Zisser, David Kerr and Eyal Dassau
  
  Diabetes Care 2014 Oct; 37 (10): e228. https://doi.org/10.2337/dc14-1693
  
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- Open Access
  Comment on Grunberger “Insulin Analogs—Are They Worth It? Yes!” Diabetes Care 2014;37:1767–1770 and Davidson “Insulin Analogs—Is There a Compelling Case to Use Them? No!” Diabetes Care 2014;37:1771–1774
  Dario Giugliano, Michela Petrizzo, Maria Ida Maiorino, Giuseppe Bellastella and Katherine Esposito
  
  Diabetes Care 2014 Oct; 37 (10): e229-e230. https://doi.org/10.2337/dc14-1390
  
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- Open Access
  Response to Comment on Grunberger “Insulin Analogs—Are They Worth It? Yes!” Diabetes Care 2014;37:1767–1770 and Davidson “Insulin Analogs—Is There a Compelling Case to Use Them? No!” Diabetes Care 2014;37:1771–1774
  Mayer B. Davidson
  
  Diabetes Care 2014 Oct; 37 (10): e231. https://doi.org/10.2337/dc14-1605
  
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- Open Access
  Response to Comment on Grunberger “Insulin Analogs—Are They Worth It? Yes!” Diabetes Care 2014;37:1767–1770 and Davidson “Insulin Analogs—Is There a Compelling Case to Use Them? No!” Diabetes Care 2014;37:1771–1774
  George Grunberger
  
  Diabetes Care 2014 Oct; 37 (10): e232. https://doi.org/10.2337/dc14-1643
  
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Table of Contents

In This Issue

Editorial

Perspectives in Care

Clinical Care/Education/Nutrition/Psychosocial Research

Epidemiology/Health Services Research

Emerging Technologies and Therapeutics

Pathophysiology/Complications

Cardiovascular and Metabolic Risk

Novel Communications in Diabetes

Position Statement

Scientific Statement

Consensus Report

Review

Erratum

Issues and Events

e-Letters

Observations

Comments and Responses

In this Issue

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