Diabetes Care: 39 (2)

February 01 2016; volume 39 issue 2

In This Issue

Open Access
In This Issue of Diabetes Care
Diabetes Care 2016 Feb; 39 (2): 177-178. https://doi.org/10.2337/dc16-ti02

Perspectives in Care

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The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell–Centric Classification Schema
Stanley S. Schwartz, Solomon Epstein, Barbara E. Corkey, Struan F.A. Grant, James R. Gavin III and Richard B. Aguilar

Diabetes Care 2016 Feb; 39 (2): 179-186. https://doi.org/10.2337/dc15-1585

Commentary

Open Access
Mechanism of Metformin: A Tale of Two Sites
Ruisheng Song

Diabetes Care 2016 Feb; 39 (2): 187-189. https://doi.org/10.2337/dci15-0013

Clinical Care/Education/Nutrition/Psychosocial Research

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Health Care Transition in Young Adults With Type 1 Diabetes: Perspectives of Adult Endocrinologists in the U.S.
Katharine C. Garvey, Gabriela H. Telo, Joseph S. Needleman, Peter Forbes, Jonathan A. Finkelstein and Lori M. Laffel

Diabetes Care 2016 Feb; 39 (2): 190-197. https://doi.org/10.2337/dc15-1775
Open Access
The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation: Results From Short-term Pharmacokinetic and 12-Week Dose-Ranging Studies
John B. Buse, Ralph A. DeFronzo, Julio Rosenstock, Terri Kim, Colleen Burns, Sharon Skare, Alain Baron and Mark Fineman

Diabetes Care 2016 Feb; 39 (2): 198-205. https://doi.org/10.2337/dc15-0488
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Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blind, Parallel-Group, Randomized Trial
Thomas Idorn, Filip K. Knop, Morten B. Jørgensen, Tonny Jensen, Marsela Resuli, Pernille M. Hansen, Karl B. Christensen, Jens J. Holst, Mads Hornum and Bo Feldt-Rasmussen

Diabetes Care 2016 Feb; 39 (2): 206-213. https://doi.org/10.2337/dc15-1025
Open Access
Liraglutide Reduces CNS Activation in Response to Visual Food Cues Only After Short-term Treatment in Patients With Type 2 Diabetes
Jennifer S. ten Kulve, Dick J. Veltman, Liselotte van Bloemendaal, Frederik Barkhof, Madeleine L. Drent, Michaela Diamant and Richard G. IJzerman

Diabetes Care 2016 Feb; 39 (2): 214-221. https://doi.org/10.2337/dc15-0772
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Efficacy and Safety of Liraglutide Versus Placebo as Add-on to Glucose-Lowering Therapy in Patients With Type 2 Diabetes and Moderate Renal Impairment (LIRA-RENAL): A Randomized Clinical Trial
Melanie J. Davies, Stephen C. Bain, Stephen L. Atkin, Peter Rossing, David Scott, Minara S. Shamkhalova, Heidrun Bosch-Traberg, Annika Syrén and Guillermo E. Umpierrez

Diabetes Care 2016 Feb; 39 (2): 222-230. https://doi.org/10.2337/dc14-2883
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A Phase 2, Randomized, Dose-Finding Study of the Novel Once-Weekly Human GLP-1 Analog, Semaglutide, Compared With Placebo and Open-Label Liraglutide in Patients With Type 2 Diabetes
Michael A. Nauck, John R. Petrie, Giorgio Sesti, Edoardo Mannucci, Jean-Pierre Courrèges, Marie L. Lindegaard, Christine B. Jensen and Stephen L. Atkin, for the Study 1821 Investigators

Diabetes Care 2016 Feb; 39 (2): 231-241. https://doi.org/10.2337/dc15-0165
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Effect of the GLP-1 Receptor Agonist Lixisenatide on Counterregulatory Responses to Hypoglycemia in Subjects With Insulin-Treated Type 2 Diabetes
Johan Farngren, Margaretha Persson and Bo Ahrén

Diabetes Care 2016 Feb; 39 (2): 242-249. https://doi.org/10.2337/dc15-1274
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Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes
Angus G. Jones, Timothy J. McDonald, Beverley M. Shields, Anita V. Hill, Christopher J. Hyde, Bridget A. Knight and Andrew T. Hattersley, for the PRIBA Study Group

Diabetes Care 2016 Feb; 39 (2): 250-257. https://doi.org/10.2337/dc15-0258

Epidemiology/Health Services Research

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Adherence to Oral Glucose-Lowering Therapies and Associations With 1-Year HbA_1c: A Retrospective Cohort Analysis in a Large Primary Care Database
Andrew J. Farmer, Lauren R. Rodgers, Mike Lonergan, Beverley Shields, Michael N. Weedon, Louise Donnelly, Rury R. Holman, Ewan R. Pearson and Andrew T. Hattersley, for the MASTERMIND Consortium

Diabetes Care 2016 Feb; 39 (2): 258-263. https://doi.org/10.2337/dc15-1194
Open Access
Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study
Michael R. Rickels, Katrina J. Ruedy, Nicole C. Foster, Claude A. Piché, Hélène Dulude, Jennifer L. Sherr, William V. Tamborlane, Kathleen E. Bethin, Linda A. DiMeglio, R. Paul Wadwa, Andrew J. Ahmann, Michael J. Haller, Brandon M. Nathan, Santica M. Marcovina, Emmanouil Rampakakis, Linyan Meng and Roy W. Beck, for the T1D Exchange Intranasal Glucagon Investigators

Diabetes Care 2016 Feb; 39 (2): 264-270. https://doi.org/10.2337/dc15-1498
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A1C Combined With Glycated Albumin Improves Detection of Prediabetes in Africans: The Africans in America Study
Anne E. Sumner, Michelle T. Duong, Paola C. Aldana, Madia Ricks, Marshall K. Tulloch-Reid, Jay N. Lozier, Stephanie T. Chung and David B. Sacks

Diabetes Care 2016 Feb; 39 (2): 271-277. https://doi.org/10.2337/dc15-1699
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Prevalence of Diabetes and Diabetic Nephropathy in a Large U.S. Commercially Insured Pediatric Population, 2002–2013
Lin Li, Susan Jick, Stefanie Breitenstein and Alexander Michel

Diabetes Care 2016 Feb; 39 (2): 278-284. https://doi.org/10.2337/dc15-1710
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Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study
Mary E. Lacy, Gregory A. Wellenius, Mercedes R. Carnethon, Eric B. Loucks, April P. Carson, Xi Luo, Catarina I. Kiefe, Annie Gjelsvik, Erica P. Gunderson, Charles B. Eaton and Wen-Chih Wu

Diabetes Care 2016 Feb; 39 (2): 285-291. https://doi.org/10.2337/dc15-0509

Pathophysiology/Complications

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Effect of Bariatric Surgery on Adipose Tissue Glucose Metabolism in Different Depots in Patients With or Without Type 2 Diabetes
Prince Dadson, Linda Landini, Mika Helmiö, Jarna C. Hannukainen, Heidi Immonen, Miikka-Juhani Honka, Marco Bucci, Nina Savisto, Minna Soinio, Paulina Salminen, Riitta Parkkola, Jussi Pihlajamäki, Patricia Iozzo, Ele Ferrannini and Pirjo Nuutila

Diabetes Care 2016 Feb; 39 (2): 292-299. https://doi.org/10.2337/dc15-1447

Meta-analysis

Open Access
Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia
Saion Chatterjee, Sanne A.E. Peters, Mark Woodward, Silvia Mejia Arango, G. David Batty, Nigel Beckett, Alexa Beiser, Amy R. Borenstein, Paul K. Crane, Mary Haan, Linda B. Hassing, Kathleen M. Hayden, Yutaka Kiyohara, Eric B. Larson, Chung-Yi Li, Toshiharu Ninomiya, Tomoyuki Ohara, Ruth Peters, Tom C. Russ, Sudha Seshadri, Bjørn H. Strand, Rod Walker, Weili Xu and Rachel R. Huxley

Diabetes Care 2016 Feb; 39 (2): 300-307. https://doi.org/10.2337/dc15-1588

Position Statement

Open Access
Management of Diabetes in Long-term Care and Skilled Nursing Facilities: A Position Statement of the American Diabetes Association
Medha N. Munshi, Hermes Florez, Elbert S. Huang, Rita R. Kalyani, Maria Mupanomunda, Naushira Pandya, Carrie S. Swift, Tracey H. Taveira and Linda B. Haas

Diabetes Care 2016 Feb; 39 (2): 308-318. https://doi.org/10.2337/dc15-2512

Statement of Retraction

Open Access
Statement of Retraction. Nuts as a Replacement for Carbohydrates in the Diabetic Diet. Diabetes Care 2011;34:1706–1711. DOI: 10.2337/dc11-0338
David J.A. Jenkins, Cyril W.C. Kendall, Monica S. Banach, Korbua Srichaikul, Edward Vidgen, Sandy Mitchell, Tina Parker, Stephanie Nishi, Balachandran Bashyam, Russell de Souza, Christopher Ireland and Robert G. Josse

Diabetes Care 2016 Feb; 39 (2): 319. https://doi.org/10.2337/dc16-rt02

Issues and Events

Open Access
Issues and Events
Diabetes Care 2016 Feb; 39 (2): 320. https://doi.org/10.2337/dc16-ie02

e-Letters

Observations
- Open Access
  Could the Discrepancy in Perceived Emotional Care Received and Provided Be a Barrier to Active Diabetes Self-management? Insights From the Second Diabetes Attitudes, Wishes and Needs (DAWN2) Study
  Katharine D. Barnard, Richard I.G. Holt, Pamela A. Dyson, Michael H. Cummings, Naresh Kanumilli, Simon O’Neill and Gwen Hall
  
  Diabetes Care 2016 Feb; 39 (2): e20-e21. https://doi.org/10.2337/dc15-0674
- Open Access
  Effects of GLP-1 Receptor Agonists on Heart Rate and the Autonomic Nervous System Using Holter Electrocardiography and Power Spectrum Analysis of Heart Rate Variability
  Yuki Nakatani, Atsuhiko Kawabe, Mihoko Matsumura, Yoshimasa Aso, Takanori Yasu, Nobuyuki Banba and Takaaki Nakamoto
  
  Diabetes Care 2016 Feb; 39 (2): e22-e23. https://doi.org/10.2337/dc15-1437
Comments and Responses
- Open Access
  Comment on Nunley et al. Clinically Relevant Cognitive Impairment in Middle-Aged Adults With Childhood-Onset Type 1 Diabetes. Diabetes Care 2015;38:1768–1776
  Kiki van Broekhoven and Giesje Nefs
  
  Diabetes Care 2016 Feb; 39 (2): e24. https://doi.org/10.2337/dc15-2163
- Open Access
  Response to Comment on Nunley et al. Clinically Relevant Cognitive Impairment in Middle-Aged Adults With Childhood-Onset Type 1 Diabetes. Diabetes Care 2015;38:1768–1776
  Karen A. Nunley, Christopher M. Ryan, Judith A. Saxton, Tina Costacou, Trevor J. Orchard and Caterina Rosano
  
  Diabetes Care 2016 Feb; 39 (2): e25. https://doi.org/10.2337/dci15-0028
- Open Access
  Comment on Hoffstad et al. Diabetes, Lower-Extremity Amputation, and Death. Diabetes Care 2015;38:1852–1857
  Jaap J. van Netten, Lauren V. Fortington and Robert J. Hinchliffe
  
  Diabetes Care 2016 Feb; 39 (2): e26. https://doi.org/10.2337/dc15-1972
- Open Access
  Response to Comment on Hoffstad et al. Diabetes, Lower-Extremity Amputation, and Death. Diabetes Care 2015;38:1852–1857
  David J. Margolis and Ole Hoffstad
  
  Diabetes Care 2016 Feb; 39 (2): e27. https://doi.org/10.2337/dci15-0025
- Open Access
  Comment on Jakubowicz et al. Fasting Until Noon Triggers Increased Postprandial Hyperglycemia and Impaired Insulin Response After Lunch and Dinner in Individuals With Type 2 Diabetes: A Randomized Clinical Trial. Diabetes Care 2015;38:1820–1826
  Om P. Ganda
  
  Diabetes Care 2016 Feb; 39 (2): e28. https://doi.org/10.2337/dc15-2362

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Table of Contents

In This Issue

Perspectives in Care

Commentary

Clinical Care/Education/Nutrition/Psychosocial Research

Epidemiology/Health Services Research

Pathophysiology/Complications

Meta-analysis

Position Statement

Statement of Retraction

Issues and Events

e-Letters

Observations

Comments and Responses

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