Biologic Activities of Biosynthetic Human Insulin in Healthy Volunteers and Insulin-dependent Diabetic Patients Monitored by the Artificial Endocrine Pancreas
- Sotos Raptis,
- Constantine Karaiskos,
- Franz Enzmann,
- Dimitrios Hatzidakis,
- Christos Zoupas,
- Athanasios Souvatzoglou,
- E Diamantopoulos and
- Spyridon Moulopoulos
- Diabetes and Artificial Pancreas Unit, Department of Clinical Therapeutics, Athens University Greece
- Address reprint requests to S. Raptis, P.O. Box 3127, Athens 606, Greece.
Abstract
This study investigates and compares biosynthetic human insulin (BHI) and purified pork insulin, in healthy volunteers and in insulin-dependent diabetic patients, in terms of biologic action, capacity for controlling diabetic patients, and the requirements of the patients on each insulin. The possible importance of this new insulin in the improved long-term control of diabetic patients led to the experimental design of this protocol.
- Copyright © 1981 by the American Diabetes Association
