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Binding of Insulin to Rat Pancreatic Islets: Comparison Between Pancreatic Human Insulin and Biosynthetic Human Insulin

  1. E J Verspohl and
  2. H P T Ammon
  1. Department of Pharmacology, Institute of Pharmaceutical Sciences Tubingen, Germany
  1. Address reprint requests to E. J. Verspohl at the above address.

Abstract

Human pancreatic insulin, biosynthetic human insulin (BHI), and pork insulin were compared in terms of their binding characteristics to insulin receptors on rat pancreatic islets. There was no difference in binding or on biologic effect, i.e., ability to inhibit insulin secretion.

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