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Receptor Binding and Effect of Biosynthetic Human Insulin on 2-Deoxyglucose Transport

  1. Tj Wieringa,
  2. J P M Van Putten,
  3. M Van Dijk-Besling and
  4. H M J Krans
  1. Diabetes Research Laboratory, Department of Endocrinology and Metabolic Diseases; and the Department of Chemical Pathology, University Hospital 2333 AA Leiden, The Netherlands
  1. Address reprint requests to Tj. Wieringa, The Diabetes Research Laboratory, Department of Endocrinology and Metabolic Diseases, University Hospital, 2333 AA Leiden, The Netherlands.

Abstract

Biosynthetic human insulin (BHI) and purified pork insulin (PPI) were compared for binding properties and stimulatory effect on 2-deoxyglucose transport in isolated rat fat cells. No difference between these types of insulin could be demonstrated.

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