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Improvement of Lipid Status in Diabetic Boys: The 1971 and 1979 Joslin Camp Lipid Levels

  1. Marc H Blanc,
  2. Om P Ganda,
  3. Ray E Gleason and
  4. J Stuart Soeldner
  1. Elliott P. Joslin Research Laboratory in the Department of Medicine, Harvard Medical School; the Brigham and Women's Hospital, the Joslin Clinic and the Joslin Diabetes Center, Inc.; and the New England Deaconess Hospital Boston
  1. Address reprint requests to J. Stuart Soeldner, M.D., Elliott P. Joslin Research Laboratory, Harvard Medical School, One Joslin Place, Boston, MA 02215.

Abstract

Since 1972, young type I diabetic patients seen by Joslin Clinic physicians have been advised to use a low cholesterol diet with a high proportion of polyunsaturated fat. Mean fasting cholesterol and triglyceride levels at admission to the Joslin Boys Camp for the years 1971 (N = 129) and 1979 (N = 79) were compared. In 1979, the mean cholesterol level was lower by 44 mg/dl (P < 0.001) and the mean triglyceride by 21 mg/dl (P < 0.001) compared with 1971. The incidence of hyperlipoproteinemia decreased from 21.6% to 7.6% with a complete disappearance of types IV and V during the same period. A decrease in the development of arteriosclerotic cardiovascular diseases in type I diabetic patients might be anticipated from this diet modification.

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