Diabetes Mellitus and Optic Atrophy in Two Siblings: A Report on a New Association and a Review of the Literature
Abstract
Two siblings with diabetes mellitus and optic atrophy (Wolfram syndrome) are described. As often noted, they also had atonic urinary bladders. Only one of the siblings had some impairment of hearing. Other findings not previously reported that appeared in each subject were esophageal dysphagia and vertigo. An autopsy in one revealed brain stem hypoplasia and thinning and flattening of the optic nerves with atrophy of the lateral geniculate bodies.
- Copyright © 1983 by the American Diabetes Association
