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High Prevalence of Maturity-onset Diabetes of the Young (MODY) Among Indians

  1. Viswanathan Mohan, M.D.,
  2. Ambady Ramachandran, M.D.,
  3. Chamukuttan Snehalatha, M.Sc., D.Phil.,
  4. Rema Mohan, M.B.B.S.,
  5. Gopalan Bharani, M.O. and
  6. Moopil Viswanathan, M.D.
  1. Diabetes Research Center 5, Main Road, Royapuram, Madras-600 013, India
  1. Part of this study was presented at the Forty-Fourth Annual Meeting of the American Diabetes Association, Las Vegas, Nevada, June 1984.

Abstract

This article describes the high prevalence of maturity-onset diabetes in the young (MODY) in an Indian clinic population of diabetic patients. MODY appears to be more common among Indians than among Caucasians. Only 27% of MODY patients had definite autosomal-dominant inheritance. In 73% the mode of inheritance was not definite. Microvascular complications were common and macrovascular complications rare. The high prevalence of MODY in this diabetes clinic might suggest an ethnic variation in diabetes.

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