Postsplenectomy Sepsis Caused by Group B Streptococcus (S. agalactiae) in an Adult Patient with Diabetes Mellitus
- Hamilton R Fish, M.D.,
- John K S Chia, M.D. and
- K M Mohamed Shakir, M.D., F.A.C.P.
- Branches of Endocrinology and Metabolism, Department of Internal Medicine, Navy Hospital, National Capital Region, and the Uniformed Services University of the Health Sciences Bethesda, Maryland
- Infectious Diseases, Department of Internal Medicine, Navy Hospital, National Capital Region, and the Uniformed Services University of the Health Sciences Bethesda, Maryland
- Address reprint requests to Hamilton R. Fish, M.D., Internal Medicine Dept., Box 4603, Naval Hospital, Oakland, California 94627–5000.
Abstract
Overwhelming postsplenectomy infection (OPSI) due to group B streptococcus developed in an insulin-dependent diabetic patient. The illness began with nonspecific symptoms, followed rapidly by hypotension and disseminated intravascular coagulation. The early institution of appropriate antibiotics, fluid replacement and pressor agents resulted in a favorable clinical outcome. The association of group B streptococcal infection and diabetes mellitus is discussed. The defects in normal host defenses associated with asplenic state and diabetes mellitus are further emphasized. This is the first case report linking the association of OPSI, diabetes mellitus and group B streptococcal septicemia.
- Copyright © 1985 by the American Diabetes Association
