Can self-rated health be used for risk prediction in patients with type 2 diabetes?

  1. Alison J. Hayes, Ph.D (alisonh{at}health.usyd.edu.au)1,
  2. Philip M. Clarke, Ph.D1,
  3. Paul G. Glasziou, Ph.D2,
  4. R. John Simes, FRACP3,
  5. Paul L. Drury, FRACP4 and
  6. Anthony C. Keech, FRACP3
  1. 1. Public Health, University of Sydney, NSW Australia
  2. 2. Primary Care, University of Oxford, United Kingdom
  3. 3. NHMRC Clinical Trials Centre, University of Sydney, NSW, Australia
  4. 4. Auckland Diabetes Centre, Auckland, New Zealand

    Abstract

    Objective: To investigate whether self-rated health using the EQ VAS is an independent predictor of vascular events and major complications in people with type 2 diabetes after controlling for standard clinical risk factors.

    Research design and methods: The study is based on 7348 people with a mean follow-up of 2.4 years after completing the EQ-5D questionnaire. We used Cox proportional hazards modeling to estimate hazard ratios associated with EQ VAS scores after controlling for baseline covariates: age, sex, smoking status, diabetes duration, HbA1c, systolic blood pressure, body mass index, plasma lipids and prior clinical history.

    Results: A 10 point higher EQ VAS score was associated with a 6% (95% CI:1,11) lower risk of vascular events, and a 22% (95% CI:15,28) lower risk of diabetic complications.

    Conclusions: Self-rated health using the EQ VAS provides additional information on patient risk that is over and above that determined from clinical risk factors.

    Footnotes

      • Received July 19, 2007.
      • Accepted December 27, 2007.