Association between Raised Blood Pressure and Dysglycemia in Hong Kong Chinese

  1. Bernard My Cheung, PhD (b.cheung{at}bham.ac.uk)1,2,
  2. Nelson Wat MS, FRCP1,
  3. Annette WK Tso, MRCP(UK)1,
  4. Sidney Tam3,
  5. FACB G Neil Thomas, PhD4,
  6. Gabriel M Leung, MD5,
  7. Hung Fat Tse, MD1,
  8. Jean Woo, MD6,
  9. Edward D Janus, MD7,
  10. Chu Pak Lau, MD1,
  11. Tai Hing Lam, MD5 and
  12. Karen SL Lam, MD1
  1. 1Department of Medicine, University of Hong Kong
  2. 2Department of Clinical Pharmacology, University of Birmingham, England
  3. 3Clinical Biochemistry Unit, Queen Mary Hospital, Hong Kong
  4. 4Department of Public Health and Epidemiology, University of Birmingham, England
  5. 5Department of Community Medicine, University of Hong Kong
  6. 6Department of Medicine and Therapeutics, Chinese University of Hong Kong
  7. 7Department of Medicine, Western Hospital, Footscray, VIC 3011, Australia

    Abstract

    Objective: To investigate the association between raised blood pressure and dysglycemia.

    Research design and methods: We studied this association in 1862 subjects in the Hong Kong Cardiovascular Risk Factor Prevalence Study Cohort. We determined the factors predicting the development of diabetes and hypertension in 1496 subjects who did not have either condition at baseline.

    Results: Diabetes and hypertension were both related to age, obesity indices, blood pressure, glucose, HDL, and triglycerides. 58% of people with diabetes had raised blood pressure. 56% of people with hypertension had dysglycemia. BMI and blood glucose 2 hours after 75g oral glucose predicted new-onset diabetes. Age, systolic blood pressure and 2-hour glucose predicted new-onset hypertension. BMI, systolic blood pressure, and 2-hour glucose predicted the development of diabetes and hypertension together.

    Conclusions: Diabetes and hypertension share common etiological factors. Patients with diabetes or hypertension should be screened and managed for the precursor of the other condition.

    Footnotes

      • Received February 26, 2008.
      • Accepted June 4, 2008.

    This Article

    1. Published online before print June 12, 2008, doi: 10.2337/dc08-0405
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