Normal glucose values are associated with a lower risk of mortality in hospitalized patients
- Alberto Bruno, MD (abruno{at}molinette.piemonte.it)1,
- Dario Gregori, PHD2,
- Antonio Caropreso, BD3,
- Fulvio Lazzarato, BS4,
- Michele Petrinco, BS2 and
- Eva Pagano, BS4
- 1Diabetologia ASO San Giovanni Battista of Turin
- 2Department of Public Health and Microbiology, University of Turin
- 3Central Laboratory ASO San Giovanni Battista of Turin
- 4Unit of cancer epidemiology - CPO Piemonte - University of Turin
Abstract
Objective- Hyperglycemia is a common condition in hospitalized patients. The aim of the study was to investigate the relationships between glycemia upon admission and mortality in a heterogeneous group of adult patients.
Research Design and Methods- The three-year records released from a general hospital were associated to plasma glucose dataset of its general laboratory. A matched case control study was implemented (3338 cases-controls). All Patient Refined Diagnosis Related Groups and the Relative Risk of Death were the matching criteria. A multivariate conditional logistic regression model was used to evaluate the associations between death and glycemia.
Results- Higher in-hospital mortality was associated with hyperglycemia or hypoglycemia while the lower risk was observed for values between 78 and 101 mg/dl.
Conclusions- Our data confirm the relation between glycemia upon admission and mortality and suggest that slightly increased or decreased plasma glucose can be linked with increased mortality risks.
Footnotes
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- Received April 11, 2008.
- Accepted August 11, 2008.
- Copyright © American Diabetes Association











