Reduced 10-year Risk of CHD in Patients who Participated in Community-based DPP: The DEPLOY Pilot Study
- Elaine R. Lipscomb, Ph.D. (elaine.lipscomb{at}va.gov)1,
- Emily A. Finch, M.A.2,
- Edward Brizendine, M.S.2,
- Chandan K. Saha, Ph.D.2,
- Laura M. Hays, R.N., Ph.D.3 and
- Ronald T. Ackermann, M.D., M.P.H.2
- 1Roudebush Veterans Affairs Medical Center, Health Services Research & Development Center of Excellence for Implementing Evidence-Based Practice, Indianapolis, Indiana
- 2Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
- 3School of Nursing, Indiana University, Indianapolis, Indiana
Abstract
Background: We evaluated if participation in a community-based, group diabetes prevention program led to relative changes in composite 10-year CHD risk for overweight adults with abnormal glucose metabolism.
Research Design and Methods: We used the United Kingdom Prospective Diabetes Program (UKPDS) engine to estimate CHD risk for group-lifestyle and brief counseling (control) groups. Between-group risk changes after 4 and 12-months were compared using analysis of co-variance (ANCOVA).
Results: Baseline 10-year risk was similar between treatment groups (p = 0.667). At 4- and 12-months, the intervention group experienced significant decreases in 10-year risk from baseline (−3.28%, p < 0.001 and −2.23%, p =0.037) compared to controls (−0.78%, p =0.339 and +1.88%, p =0.073). Between-group differences were statistically significant and increased from 4- to 12-month visits.
Conclusions: Community-based delivery of the DPP lifestyle intervention could be a promising strategy to prevent both CHD and type 2 diabetes in adults with pre-diabetes.
Footnotes
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- Received September 3, 2008.
- Accepted December 15, 2008.
- Copyright © American Diabetes Association
