Risk factors for type 2 diabetes in a 6th grade multi-racial cohort: the HEALTHY study

  1. The HEALTHY Study Group,
  2. Francine R. Kaufman, MD (chair),
  3. Kathryn Hirst, PhD (khirst{at}bsc.gwu.edu),
  4. Barbara Linder, MD PhD,
  5. Tom Baranowski, PhD,
  6. Dan M. Cooper, MD,
  7. Gary Foster, PhD,
  8. Linn Goldberg, MD,
  9. Joanne Harrell, PhD,
  10. Marsha D. Marcus, PhD and
  11. Roberto Treviño, MD
  1. Childrens Hospital Los Angeles
  2. George Washington University
  3. National Institutes of Diabetes and Digestive and Kidney Diseases
  4. Baylor College of Medicine
  5. University of California at Irvine
  6. Temple University
  7. Oregon Health & Science University
  8. University of North Carolina at Chapel Hill
  9. University of Pittsburgh
  10. University of Texas Health Science Center at San Antonio

    Abstract

    Objective: HEALTHY is a 3-year middle school intervention program designed to reduce risk factors for type 2 diabetes. The prevalence of diabetes risk factors at baseline in a cohort of 6358 sixth grade students is reported.

    Research Design and Methods: 42 schools at 7 US sites were randomly assigned to intervention or control. Students participated in baseline data collection during fall 2006.

    Results: Overall, 49.3% of children had BMI ≥ 85th percentile, 16.0% had fasting blood glucose ≥ 100 mg/dL (< 1% had fasting blood glucose ≥ 126 mg/dL), and 6.8% had fasting insulin ≥ 30 μU/mL. Hispanic youth were likelier to have BMI, glucose, and insulin levels above these thresholds compared to Blacks and Whites.

    Conclusions: Sixth grade students in schools with large minority populations have high levels of risk factors for type 2 diabetes. The HEALTHY intervention was designed to modify these risk factors to reduce diabetes incidence.

    Footnotes

      • Received September 26, 2008.
      • Accepted January 20, 2009.