Obstructive Sleep Apnea among Obese Patients with Type 2 Diabetes
- Gary D. Foster, PhD (gfoster{at}temple.edu)1,
- Mark H. Sanders, MD3,
- Richard Millman, MD4,
- Gary Zammit, MD5,
- Kelley E. Borradaile, PhD1,
- Anne B. Newman, MD3,
- Thomas A Wadden, PhD.2,
- David Kelley, MD3,
- Rena R. Wing, Ph.D.4,
- F. Xavier Pi Sunyer, MD6,
- Valerie Darcey, MS2,
- Samuel T. Kuna, MD2 and
- the Sleep AHEAD Research Group
- 1Temple University
- 2University of Pennsylvania
- 3University of Pittsburgh
- 4Brown University
- 5Clinilabs
- 6Columbia University
Abstract
Objective: To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes.
Research Design and Methods: Unattended polysomnography was performed in 306 participants.
Results: Over 86% of participants had OSA with an apnea-hypopnea index (AHI) ≥ 5 events/hr. The mean AHI was 20.5±16.8 events/hr. 30.5% of the participants had moderate (15 ≤ AHI < 30), and 22.6% had severe OSA (AHI ≥ 30). Waist circumference (OR, 1.1; 95% CI 1.0-1.1; p=.03) was significantly related to the presence of OSA. Severe OSA was most likely in those with a higher BMI (OR, 1.1; 95% CI: 1.0-1.2; p= .03).
Conclusions: Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among those with higher waist circumference and BMI.
Footnotes
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- Received September 26, 2008.
- Accepted February 28, 2009.
- Copyright © American Diabetes Association
