Obstructive Sleep Apnea among Obese Patients with Type 2 Diabetes

  1. Gary D. Foster, PhD (gfoster{at}temple.edu)1,
  2. Mark H. Sanders, MD3,
  3. Richard Millman, MD4,
  4. Gary Zammit, MD5,
  5. Kelley E. Borradaile, PhD1,
  6. Anne B. Newman, MD3,
  7. Thomas A Wadden, PhD.2,
  8. David Kelley, MD3,
  9. Rena R. Wing, Ph.D.4,
  10. F. Xavier Pi Sunyer, MD6,
  11. Valerie Darcey, MS2,
  12. Samuel T. Kuna, MD2 and
  13. the Sleep AHEAD Research Group
  1. 1Temple University
  2. 2University of Pennsylvania
  3. 3University of Pittsburgh
  4. 4Brown University
  5. 5Clinilabs
  6. 6Columbia University

    Abstract

    Objective: To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes.

    Research Design and Methods: Unattended polysomnography was performed in 306 participants.

    Results: Over 86% of participants had OSA with an apnea-hypopnea index (AHI) ≥ 5 events/hr. The mean AHI was 20.5±16.8 events/hr. 30.5% of the participants had moderate (15 ≤ AHI < 30), and 22.6% had severe OSA (AHI ≥ 30). Waist circumference (OR, 1.1; 95% CI 1.0-1.1; p=.03) was significantly related to the presence of OSA. Severe OSA was most likely in those with a higher BMI (OR, 1.1; 95% CI: 1.0-1.2; p= .03).

    Conclusions: Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among those with higher waist circumference and BMI.

    Footnotes

      • Received September 26, 2008.
      • Accepted February 28, 2009.

    This Article

    1. Diabetes Care
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