Association of smoking status, weight change, and incident metabolic syndrome in men: A 3-year follow-up study
- Byung Jin Kim, MD, PhD (bjjake.kim{at}samsung.com),
- Bum Soo kim, MD, PhD,
- Ki Chul Sung, MD, PhD,
- Jin Ho Kang, MD, PhD,
- Man Ho Lee, MD, PhD and
- Jung Ro Park, MD, PhD
- Division of Cardiology, Department of Internal Medicine, Kangbuk SaMetSung Hospital, Sungkyunkwan University School of Medicine
Abstract
Objective: We investigated the incidence of MetS and assessed the effect of smoking status and weight change on incident MetS.
Research Design and Methods: This study included 4542 men without MetS at baseline who were followed-up for an average of 3-year. Subjects were divided into four categories according to their smoking status at baseline and at the 3-year follow-up.
Results: The overall incidence of MetS was 10.6%; 8.0% in non-smokers, 7.1% in new-smokers, 17.1% in ex-smokers, and 13.9% in sustained-smokers (p<0.001). In a multivariate regression model, ex-smokers had significant increased odds for incident MetS of 1.45 (95% CI 1.06 to 1.98), as compared with sustained-smokers. This was no longer significant after including weight change.
Conclusions: Smoking cessation within 3 years may be a higher risk factor for incident MetS than sustained smoking, indicating that weight control in ex-smokers is critical to attenuate the additional risk for incident MetS.
Footnotes
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- Received January 13, 2009.
- Accepted April 14, 2009.
- Copyright © American Diabetes Association
