Efficacy of a behavioral lifestyle intervention group program (PREDIAS) for the prevention of type 2 diabetes.
- Bernhard Kulzer, PhD1,
- Norbert Hermanns, PhD (hermanns{at}diabetes-zentrum.de)1,
- Daniela Gorges, MA1,
- Peter Schwarz, MD2 and
- Thomas Haak, PhD1
- 1Research Institute of the Diabetes Academy Mergentheim & Diabetes Centre Mergentheim, Bad Mergentheim, Germany
- 2Department of Medicine, University of Dresden, Carl Gustav Carus, Dresden, Germany
Abstract
Introduction: The objective of this randomized, prospective trial was to evaluate the efficacy of a group program (PREDIAS) for diabetes prevention.
Design and Methods: PREDIAS consists of 12 lessons and aims at the modification of lifestyle. The control group (CG) received written information about diabetes prevention. In this study, a total of 182 persons with an elevated diabetes risk participated (age 56.3 ±10.1 yrs; 43% female; BMI 31.5 ±5.3 kg/m2).
Results: After 12 months, weight loss was significantly higher (p = .001) in PREDIAS than in the CG (−3.8 ±5.2 kg vs. −1.4 ±4.09 kg). There were also significant effects (p = .001) on fasting glucose (CG +1.8 ±13.1 mg/dl vs. PREDIAS −4.3 ±11.3 mg/dl), duration of physical activity per week (CG + 17.9 ±63.8 minutes vs. PREDIAS +46.6 ±95.5 minutes; p = .03), and eating behavior.
Conclusion: PREDIAS significantly modified lifestyle factors associated with an elevated diabetes risk.
Footnotes
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- Received December 2, 2008.
- Accepted March 6, 2009.
- Copyright © American Diabetes Association
