Age-Related Differences in the Frequency of Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents

  1. The Finnish Pediatric Diabetes Register
  1. 1Department of Pediatrics, University of Oulu, Oulu University Hospital, Oulu, Finland
  2. 2National Public Health Institute, Helsinki, Finland
  3. 3Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland
  4. 4Folkhälsan Research Center, Helsinki, Finland
  5. 5Department of Pediatrics, Tampere University Hospital, Tampere, Finland


Objective — We studied the prevalence of DKA at diagnosis of type 1 diabetes in children in Finland.

Research design and methods — During 2002-2005 data on virtually all children <15 years diagnosed with type 1 diabetes in Finland was collected (n=1656).

Results — DKA was present in 19.4% of the cases and 4.3% had severe DKA. In children aged 0–4, 5–9 and 10–14 years DKA was present in 16.5%, 14.8% and 26.4%, respectively (P<0.001). Severe DKA occurred in 3.7%, 3.1% and 5.9% (P=0.048). DKA was present in 30.1% and severe DKA in 7.8% of children <2 years.

Conclusion — The overall frequency of DKA in children is low in Finland at diagnosis of type 1 diabetes. However, both children <2 years and adolescents aged 10-14 years are at increased risk of DKA.


    • Received December 23, 2009.
    • Accepted April 1, 2010.