Overall Diet History and Reversibility of the Metabolic Syndrome Over 5 Years: The Whitehall II Prospective Cohort Study
- Tasnime N. Akbaraly, PhD (tasnime.akbaraly{at}inserm.fr)a,b,c,
- Archana Singh-Manoux, PhDa,d,e,
- Adam G. Tabak, MD PhDa,f,
- Markus Jokela, PhDg,
- Marianna Virtanen, PhDh,
- Jane E. Ferrie, PhDa,
- Michael G. Marmot, PhDa,
- Martin J. Shipley, MSca and
- Mika Kivimaki, PhDa,g,h
- (a) Department of Epidemiology and Public Health, University College London, WC1E 6BT London, United Kingdom E8
- (b) INSERM U 888, Montpellier, F-34093 France
- (c) University Montpellier I, F-34000 Montpellier, France
- (d) Centre for Research in Epidemiology & Population Health, INSERM U1018, France
- (e) Centre de Gérontologie, Hôpital Ste Périne, AP-HP, France
- (f) Semmelweis University Faculty of Medicine, 1st Department of Medicine
- (g) Department of Behavioral Sciences, University of Helsinki, Finland
- (h) Finnish Institute of Occupational Health, Helsinki, Finland
Abstract
Objective: We examined the impact of adherence to the Alternative Healthy Eating Index (AHEI), a set of dietary guidelines targeting major chronic diseases, on metabolic syndrome (MetS) reversion in a middle-aged population.
Research Design and Methods: Analyses were carried on the 339 participants (28% women, mean age 56.4 years) from the Whitehall II study with MetS defined by the National Cholesterol Education Program Adult treatment Panel III criteria. Reversion was defined as not having MetS after 5-years of follow-up (158 cases).
Results: After controlling for potential confounders, adherence to AHEI was associated with MetS reversion (odds ratio 1.88, 95% CI:1.04 to 3.41), predominantly in participants with central obesity and in those with high triglyceride.
Conclusions: Our findings support the benefit of adherence to AHEI dietary guidelines for individuals with MetS, especially those with central obesity or high triglyceride levels.
Footnotes
- Copyright © American Diabetes Association
