Effect of 3-Month Yoga on Oxidative Stress in Type 2 Diabetes With or Without Complications

A controlled clinical trial

  1. Vivian D’Souza, MD4
  1. 1Department of Biochemistry, Srinivas Institute of Medical Science and Research Centre, Mangalore, Karnataka, India
  2. 2Department of Medicine, Kasturba Medical College and Hospital, Manipal University, Mangalore, Karnataka, India
  3. 3Department of Community Medicine, Kasturba Medical College and Hospital, Manipal University, Mangalore, Karnataka, India
  4. 4Department of Biochemistry, Kasturba Medical College and Hospital, Manipal University, Mangalore, Karnataka, India
  1. Corresponding author: Shreelaxmi V. Hegde, shreelaxmi.hegde{at}gmail.com.

Abstract

OBJECTIVE To assess the effect of yoga on anthropometry, blood pressure, glycemic control, and oxidative stress in type 2 diabetic patients on standard care in comparison with standard care alone.

RESEARCH DESIGN AND METHODS The study involved 123 patients stratified according to groups with microvascular complications, macrovascular complications, and peripheral neuropathy and without complications and assigned to receive either standard care or standard care along with additional yoga for 3 months.

RESULTS In comparison with standard care alone, yoga resulted in significant reduction in BMI, glycemic control, and malondialdehyde and increase in glutathione and vitamin C. There were no differences in waist circumference, waist-to-hip ratio, blood pressure, vitamin E, or superoxide dismutase in the yoga group at follow-up.

CONCLUSIONS Yoga can be used as an effective therapy in reducing oxidative stress in type 2 diabetes. Yoga in addition to standard care helps reduce BMI and improve glycemic control in type 2 diabetic patients.

  • Received December 25, 2010.
  • Accepted July 1, 2011.

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This Article

  1. Diabetes Care
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