OBJECTIVE To examine the association of objectively measured participation in low levels of physical activity with incident type 2 diabetes.
RESEARCH DESIGN AND METHODS The study population included participants free of diabetes and cardiovascular disease at baseline (n = 1,826) who participated in a follow-up examination. Generalized estimating equations were used to examine the association of steps per day with incident diabetes.
RESULTS During 5 years of follow-up, 243 incident cases of diabetes were identified. When compared with participants in the lowest quartile of steps per day (<3,500 steps), participants in the upper three quartiles of steps per day had lower odds for diabetes, consistent with a threshold effect. Contrasting the three upper quartiles with the lowest quartile, the odds ratio of diabetes was 0.71 (95% CI 0.51–0.98).
CONCLUSIONS Modest levels of physical activity are associated with a lower risk of incident diabetes, compared with lower levels of activity.
- Received November 30, 2011.
- Accepted April 1, 2012.
- © 2012 by the American Diabetes Association.
Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.