Table 1 —

Distribution of HLA-DQB genotypes and non-Asp-57 gene frequencies among Yemenite Jewish diabetic patients and unrelated control subjects

Allelen (%) of patientsn (%) of control subjectsFisher’s exact test (P)Odds ratioOdds ratio 95% CI
N/N39 (88)23 (36)3.1 × 10−10186.3–51.4
N/A5 (11)45 (59)1.4 × 10−70.090.03–0.25
A/A0 8 (10)0.0260.09*
NAa83 (94)91 (60)8.2 × 10−1011.14.3–29
  • N/N, non-Asp-57 homozygosity; N/A, non-Asp-57 heterozygosity; A/A, Asp-57 homozygosity; NAa, non-Asp-57 alleles.

  • *

    * Biased due to reliance on zero-cell adjustment in computing the odds ratio.