Table 3—

Relative risk of type 2 diabetes according to linoleic acid intake, stratified by BMI and age*

Quintiles of linoleic acid intake
P for trend
1 (low)2345 (high)
Age (years)
 <65 (n=866)10.85 (0.68–1.05)0.93 (0.76–1.15)0.86 (0.70–1.07)0.74 (0.60–0.92)0.01
 ≥65 (n=449)11.34 (0.99–1.82)1.22 (0.89–1.68)1.57 (1.16–2.12)1.22 (0.89–1.68)0.16
BMI (kg/m2)
 <25.0 (n=207)10.98 (0.66–1.46)0.81 (0.53–1.24)0.82 (0.54–1.25)0.53 (0.33–0.85)0.006
 25.0–29.9 (n=677)10.93 (0.73–1.20)1.08 (0.85–1.38)1.07 (0.84–1.36)0.95 (0.74–1.22)0.90
 ≥30.0 (n=398)11.00 (0.72–1.40)1.07 (0.77–1.49)1.17 (0.84–1.62)0.95 (0.68–1.33)0.94
  • Data are RR (95% CI).

  • *

    * RRs (95% CI) were adjusted for age (5-year categories), total energy intake (quintiles), time period (6 periods), physical activity (quintiles of METs), cigarette smoking (never, past, and current smoking of 1–14, 15–24, and ≥25 cigarettes/day), alcohol consumption (0, 0.1–4, 5–14, 15–29, and ≥30 g/day), hypercholesterolemia (yes/no), hypertension (yes/no), family history of type 2 diabetes (yes/ no), intake (quintiles) of cereal fiber and magnesium, and BMI (<23.0, 23.0–23.9, 24.0–24.9, 25.0–26.9, 27.0–28.9, 29.0–30.9, 31.0–32.9, 33.0–34.9, ≥35 kg/m2), except for the stratifying variables (in the BMI-stratified analysis, categories of BMI in the multivariate model were: <23.0, 23–23.9, and 24.0–24.9 for BMI <25 kg/m2; 25.0–26.9 and 27.0–29.9 for BMI 25–30 kg/m2; 30.0–32.9, 33.0–34.9, and ≥35.0 for BMI ≥30 kg/m2: in the age-stratified analysis, categories of age in the multivariate model were: <45, 45–49, 50–54, 55–59, and 60–64 for age <65 years; and 65–69 and ≥70 for age ≥65 years). In the BMI-stratified analysis, BMI at baseline was used for stratification and adjustment. The total number of subjects is <1,321 because of missing values.