Table 2—

Retinopathy (a single three-step change on the ETDRS scale) and albuminuria (a single event >40 mg/24 h) during the first 6 years of the DCCT, by stimulated C-peptide group

Stimulated C-peptide group
All
UndetectableMinimalBaseline-onlySustained
Retinopathy
  All7.8 ± 0.5a5.7 ± 0.5b5.2 ± 0.9bc3.5 ± 0.7c6.3 ± 0.3
  Intensive6.5 ± 0.7a3.5 ± 0.5b1.8 ± 0.9bc1.4 ± 0.6c4.5 ± 0.4
  Conventional9.2 ± 0.8a7.9 ± 0.8a7.3 ± 1.4a6.3 ± 1.4a8.2 ± 0.5
Albuminuria
  All4.4 ± 0.4a2.7 ± 0.3b3.1 ± 0.7ab1.4 ± 0.4c3.3 ± 0.2
  Intensive4.0 ± 0.5a2.3 ± 0.4b1.7 ± 0.9bc0.9 ± 0.5c2.9 ± 0.3
  Conventional4.9 ± 0.6a2.9 ± 0.5b3.9 ± 1.0ab2.1 ± 0.8b3.8 ± 0.3
  • Data are rates ± SE per 100 participant-years. Rates were compared (horizontally) between stimulated C-peptide groups. For each comparison, rates with different letters were significantly different (P < 0.05), while rates sharing the same letter were indistinguishable.