Table 2—

Carotid atherosclerosis and CHD in subjects with the metabolic syndrome by WHO criteria and in the control subjects

Control subjectsMetabolic syndromeP
CA score in 1999 (mm)1.53 ± 2.02.31 ± 4.01NS
n585303
Change in CA score 1990–1995 (mm)1.21 ± 2.322.13 ± 2.780.007
n524267
Incident plaques (% of subjects)*35 (31.8–38.9)51 (45.4–56.6)0.022
n524267
Incident stenosis (% of subjects)19 (15.8–22.2)34 (28.7–39.3)0.003
n183130
Incident CHD in 1990–1995 (% of subjects)3 (2.0–4.0)8 (4.9–11.1)0.014
n585303
  • Data are means ± SD or % (95% CI). P values are adjusted for sex, age, smoking, alcohol, physical activity, social status, and LDL cholesterol.

  • *

    * Baseline atherosclerosis was an additional covariate;

  • analysis restricted to subjects with preexisting plaques;

  • subjects with preexisting CHD were not excluded, but baseline CHD was an additional covariate. CA, carotid atherosclerosis.