Table 4—

Bivariate and multivariate regression analyses of serum resistin levels on metabolic factors, inflammatory markers, and vascular reactivity*

Parametersβ1β2β3β4
Metabolic factors
    Total cholesterol (mg/dl)−0.004−0.010.020.02
    LDL cholesterol (mg/dl)0.110.110.130.13
    HDL cholesterol (mg/dl)−0.28−0.33−0.33−0.33
    Triglycerides (mg/dl)0.030.040.010.01
Inflammatory markers
    ICAM (ng/ml)−0.02−0.01−0.06−0.05
    ET1 (pg/ml)0.220.220.230.25
    TNF-α (pg/ml)0.010.01−0.02−0.01
    CRP (mg/dl)*0.280.290.380.39
    PAI-1 (ng/ml)0.120.130.100.13
    tPA (ng/ml)0.080.080.030.03
Vascular reactivity
    FR0.170.220.180.17
    FMD−0.13−0.13−0.12−0.12
    NID−0.17−0.17−0.18−0.17
    ACH%0.060.070.070.08
    NNP%0.070.060.050.05
  • β1, bivariate standardized linear regression coefficient; β2, multivariate standardized linear regression coefficient adjusted for sex; β3, multivariate standardized linear regression coefficient adjusted for sex and BMI; β4, multivariate standardized linear regression coefficient adjusted for sex, BMI, and HbA1c. FMD, flow-mediated dilation percentage increase over baseline (endothelium-dependent reactivity of macrocirculation); FR, resting brachial artery diameter (in millimeters).

  • *

    * Logarithmic transformation performed before analysis;

  • P < 0.01;

  • P < 0.025.