Table 2—

HRs of CHD death and a major CHD event and 95% CIs in Cox multivariate models for nondiabetic and diabetic subjects according to gender

Nondiabetic
Diabetic
Men
Women
P for interaction with genderMen
Women
P for interaction with gender
HR95% CIPHR95% CIPHR95% CIPHR95% CIP
CHD death
    Current smoking (no, yes)3.321.70–6.47<0.0018.781.49–51.8<0.0011.571.01–2.440.0430.750.23–2.45
    BMI (kg/m2)0.980.88–1.091.100.92–1.311.051.00–1.090.0321.010.97–1.05
    Systolic blood pressure (10 mmHg)1.221.06–1.390.0051.441.02–2.020.0360.940.84–1.051.131.04–1.220.0030.003
    Total cholesterol (mmol/l)1.351.06–1.720.0141.050.58–1.881.211.08–1.360.0011.030.92–1.160.040
    HDL cholesterol (mmol/l)0.740.28–1.910.600.05–7.360.790.43–1.440.400.20–0.820.011
    Triglycerides (mmol/l)*0.950.59–1.522.080.77–5.620.950.88–1.041.071.00–1.140.082
    Fasting glucose (mmol/l)0.540.31–0.950.0330.440.11–1.751.121.07–1.19<0.0011.101.04–1.160.001
    HbA1 (%)1.030.97–1.101.091.03–1.150.002
    Duration of diabetes (years)1.020.96–1.081.081.02–1.140.0080.067
Major CHD event
    Current smoking (no, yes)2.751.74–4.34<0.0017.572.48–23.1<0.0011.471.02–2.130.0371.470.70–3.10
    BMI (kg/m2)0.920.85–0.990.0231.070.95–1.190.0431.020.98–1.060.990.96–1.03
    Systolic blood pressure (10 mmHg)1.231.11–1.38<0.0011.160.93–1.440.990.91–1.081.141.06–1.22<0.0010.011
    Total cholesterol (mmol/l)1.361.16–1.59<0.0011.220.87–1.711.161.05–1.280.0051.040.94–1.14
    HDL cholesterol (mmol/l)0.290.14–0.620.0010.260.05–1.210.0860.690.42–1.140.480.27–0.840.010
    Triglycerides (mmol/l)*1.150.88–1.492.531.50–4.290.0040.0200.960.87–1.051.081.00–1.17
    Fasting glucose (mmol/l)0.800.55–1.150.760.33–1.741.081.03–1.120.0011.091.04–1.140.001
    HbA1 (%)1.050.98–1.131.091.03–1.150.002
    Duration of diabetes (years)1.030.98–1.071.071.02–1.120.009
  • *

    * HR (95% CI) is calculated using nontransformed values, but statistical significance is calculated using log-transformed values. The models are adjusted for age and area of residence, and variables enforced into the models are current smoking, BMI, systolic blood pressure, total cholesterol, HDL cholesterol, fasting glucose, and, additionally in type 2 diabetic subjects, duration of diabetes. Triglycerides (with HDL cholesterol omitted) and HbA1 (with fasting glucose omitted) are similarly tested in the multivariate models. P values are shown only if they are <0.10.