Table 3—

HR (95% CI) and χ2 difference, including significance, in different multivariate Cox models for diabetes-related risk of CHD death and a major CHD event in men and women

Men
Women
Men
Women
CHD death (138 of 1,012)*Major CHD event (230 of 1,012)CHD death (96 of 1,119)Major CHD event (142 of 1,119)CHD deathMajor CHD eventCHD deathMajor CHD event
Model 1: Age and area4.03 (2.74–5.91)2.92 (2.21–3.86)23.83 (10.33–54.99)14.37 (8.43–24.47)
Model 2: 1 + smoking4.15 (2.83–6.09)2.99 (2.27–3.95)23.84 (10.33–55.02)14.35 (8.43–24.43)−3.1 (NS)−2.9 (NS)0.0 (NS)0.1 (NS)
Model 3: 1 + BMI3.73 (2.52–5.52)2.86 (2.15–3.80)23.10 (9.93–53.73)14.35 (8.35–24.67)8.9 (0.003)4.9 (0.027)10.3 (0.001)10.8 (0.001)
Model 4: 1 + sBP3.96 (2.68–5.85)2.82 (2.12–3.74)20.73 (8.94–48.06)12.63 (7.34–21.61)3.3 (NS)6.1 (0.014)18.1 (<0.001)23.1 (<0.001)
Model 5: 1 + total cholesterol4.22 (2.88–6.19)3.03 (2.30–4.00)24.16 (10.48–55.74)14.57 (8.56–24.80)−4.8 (0.028)−4.6 (0.032)−0.9 (NS)−2.0 (NS)
Model 6: 1 + HDL cholesterol3.84 (2.60–5.67)2.70 (2.03–3.58)16.86 (7.14–39.84)10.49 (6.01–18.30)5.8 (0.016)10.9 (0.001)45.8 (<0.001)60.6 (<0.001)
Model 7: 1 + logTG3.46 (2.34–5.13)2.59 (1.95–3.45)18.00 (7.66–42.32)10.86 (6.24–18.89)15.0 (<0.001)16.0 (<0.001)40.0 (<0.001)56.5 (<0.001)
Model 8: 1 + BMI + sBP + HDL cholesterol + logTG3.40 (2.28–5.08)2.50 (1.87–3.35)14.47 (6.06–34.56)9.31 (5.28–16.43)18.6 (<0.001)21.3 (<0.001)60.7 (<0.001)78.8 (<0.001)
Model 9: 1 + smoking + BMI + sBP + total cholesterol + HDL cholesterol + logTG3.77 (2.52–5.65)2.75 (2.05–3.70)14.74 (6.16–35.27)9.54 (5.39–16.87)12.3 (<0.001)13.6 (<0.001)61.1 (<0.001)79.0 (<0.001)
  • Data are HRs (95% CI) or difference in χ2 values from log-likelihood test comparisons with model 1, excluding and including diabetes (corresponding P value).

  • *

    * Number of events per number of subjects. logTG, log-transformed triglycerides; sBP, systolic blood pressure.