Table 2—

SGA’s and metabolic abnormalities

DrugWeight gainRisk for diabetesWorsening lipid profile
Clozapine+++++
Olanzapine+++++
Risperidone++DD
Quetiapine++DD
Aripiprazole*+/−
Ziprasidone*+/−
  • + = increase effect; − = no effect; D = discrepant results.

  • *

    * Newer drugs with limited long-term data.